Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet
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Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and CancersThe multiple connections between pRB and cell metabolismRapid inhibition of pyruvate dehydrogenase: an initiating event in high dietary fat-induced loss of metabolic flexibility in the heartStructural and Biochemical Characterization of Human Mitochondrial Branched-chain -Ketoacid Dehydrogenase PhosphataseStructure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding PocketPDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensationFasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout miceThe role of pyruvate dehydrogenase kinase in diabetes and obesity.Role of pyruvate dehydrogenase kinase 4 in regulation of blood glucose levels.Pyruvate dehydrogenase kinase-4 contributes to the recirculation of gluconeogenic precursors during postexercise glycogen recovery.Impaired transcriptional response of the murine heart to cigarette smoke in the setting of high fat diet and obesity.Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutumGenetic inactivation of pyruvate dehydrogenase kinases improves hepatic insulin resistance induced diabetes.Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver.Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat dietImpact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetusesPyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.Mitochondrial inhibitor as a new class of insulin sensitizer.Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress.Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut.The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility.Regulation of pyruvate metabolism in metabolic-related diseases.Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins.Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice.Studies on the chemopreventive effect of carnitine on tumorigenesis in vivo, using two experimental murine models of colon cancer.
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P2860
Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet
description
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im September 2009 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2009/09/25)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/09/25)
@nl
наукова стаття, опублікована у вересні 2009
@uk
مقالة علمية (نشرت في 25-9-2009)
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name
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@ast
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@en
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@nl
type
label
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@ast
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@en
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@nl
prefLabel
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@ast
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@en
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@nl
P2860
P356
P1433
P1476
Pyruvate dehydrogenase kinase ...... s of a high-saturated fat diet
@en
P2093
Byounghoon Hwang
Robert A Harris
P2860
P304
P356
10.1042/BJ20090390
P407
P577
2009-09-25T00:00:00Z