Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration
about
Retinal iron homeostasis in health and diseaseDeletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis.Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE.Understanding and Controlling Sialylation in a CHO Fc-Fusion Process.Mice with hepcidin-resistant ferroportin accumulate iron in the retina.Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile HemochromatosisIron-mediated retinal degeneration in haemojuvelin-knockout mice.Role of iron in ischemia-induced neurodegeneration: mechanisms and insights.Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.A high serum iron level causes mouse retinal iron accumulation despite an intact blood-retinal barrierTestosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin.Hepcidin, an emerging and important player in brain iron homeostasis.A composite mouse model of aplastic anemia complicated with iron overload.
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P2860
Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration
description
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Juli 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/07/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/07/01)
@nl
наукова стаття, опублікована в липні 2011
@uk
مقالة علمية (نشرت في يوليو 2011)
@ar
name
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@ast
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@en
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@nl
type
label
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@ast
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@en
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@nl
prefLabel
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@ast
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@en
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@nl
P2093
P2860
P3181
P1476
Bmp6 regulates retinal iron ho ...... e-related macular degeneration
@en
P2093
Jared Iacovelli
Joshua L. Dunaief
Leon Kautz
Majda Hadziahmetovic
Marie-Paule Roth
Natalie Wolkow
P2860
P304
P3181
P356
10.1016/J.AJPATH.2011.03.033
P407
P577
2011-07-01T00:00:00Z