The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells
about
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptorTransactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interactionInsulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.HuR regulates p21 mRNA stabilization by UV lightHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsBasic helix-loop-helix transcription factors and enteroendocrine cell differentiationStem Cells in the Intestine: Possible Roles in Pathogenesis of Irritable Bowel SyndromeNegative regulatory effect of an oligodendrocytic bHLH factor OLIG2 on the astrocytic differentiation pathwayCyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroDThe basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimerRetinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcriptionNeuroD is required for differentiation of the granule cells in the cerebellum and hippocampusThe zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cellsEssential role of BETA2/NeuroD1 in development of the vestibular and auditory systemsDifferent levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors.Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter.Review article: transcriptional events controlling the terminal differentiation of intestinal endocrine cells.The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein bindingThe zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon.Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium.Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active beta-catenin.Role of NeuroD1 on the negative regulation of Pomc expression by glucocorticoidThe Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription.Gut endocrine cell development.Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors.Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6.CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cellsCommon regulation of growth arrest and differentiation of osteoblasts by helix-loop-helix factors.Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.The basic helix-loop-helix transcription factor NeuroD1 facilitates interaction of Sp1 with the secretin gene enhancer.Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture.Enteroendocrine cell expression of a cholecystokinin gene construct in transgenic mice and cultured cells.Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells.Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression.Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression.Constitutive overexpression of the basic helix-loop-helix Nex1/MATH-2 transcription factor promotes neuronal differentiation of PC12 cells and neurite regeneration.Developmental regulation of neurogenesis in the pluripotent human embryonal carcinoma cell line NTERA-2.Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate.The retinoblastoma protein, RB, is required for gastrointestinal endocrine cells to exit the cell cycle, but not for hormone expression.
P2860
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P2860
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells
description
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im März 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/03/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/03/15)
@nl
наукова стаття, опублікована в березні 1998
@uk
научни чланак (објављен 1998/03/15)
@sr
name
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@ast
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@en
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@nl
type
label
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@ast
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@en
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@nl
prefLabel
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@ast
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@en
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
The basic helix-loop-helix pro ...... pressing enteroendocrine cells
@en
P2093
A. B. Leiter
F. J. Naya
M. J. Tsai
P2860
P304
P3181
P356
10.1101/GAD.12.6.820
P577
1998-03-15T00:00:00Z