Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice - Wikidata - thesis-toulmin - TriplyDB

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

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Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists.Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice The spinal antinociceptive effects of cholinergic drugs in rats: receptor subtype specificity in different nociceptive tests.Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways Role of the M3 muscarinic acetylcholine receptor in beta-cell function and glucose homeostasis.Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2 Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus.Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia Muscarinic signaling in the cochlea: presynaptic and postsynaptic effects on efferent feedback and afferent excitability.Involvement of decreased muscarinic receptor function in prepulse inhibition deficits in mice reared in social isolation.Ultrasonic vocalizations induced by sex and amphetamine in M2, M4, M5 muscarinic and D2 dopamine receptor knockout mice.Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.Muscarinic receptor-mediated bronchoconstriction is coupled to caveolae in murine airways Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling Multiple muscarinic pathways mediate the suppression of voltage-gated Ca2+ channels in mouse intestinal smooth muscle cells Genome-wide association mapping of acute lung injury in neonatal inbred mice Differential regulation of primary afferent input to spinal cord by muscarinic receptor subtypes delineated using knockout mice Distinct muscarinic acetylcholine receptor subtypes contribute to stability and growth, but not compensatory plasticity, of neuromuscular synapses.Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity.Isoform specific differences in phospholipase C beta 1 expression in the prefrontal cortex in schizophrenia and suicide Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum.Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3 Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice.Modulation of pain transmission by G-protein-coupled receptors.Dynamic control of glutamatergic synaptic input in the spinal cord by muscarinic receptor subtypes defined using knockout mice A pervasive mechanism for analgesia: activation of GIRK2 channels.A novel fast mechanism for GPCR-mediated signal transduction--control of neurotransmitter release.What can transgenic and gene-targeted mouse models teach us about salivary gland physiology?Role of the cholinergic muscarinic system in bipolar disorder and related mechanism of action of antipsychotic agents.Autonomic control of blood pressure in mice: basic physiology and effects of genetic modification.The GAR-3 muscarinic receptor cooperates with calcium signals to regulate muscle contraction in the Caenorhabditis elegans pharynx Functional M3 muscarinic acetylcholine receptors in mammalian hearts M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.Cardiac effects of muscarinic receptor antagonists used for voiding dysfunction.Diabetic neuropathy enhances voltage-activated Ca2+ channel activity and its control by M4 muscarinic receptors in primary sensory neurons.Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats.Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion.Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice

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Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

http://www.wikidata.org/entity/Q28513116

description

1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 1999

@ast

im Februar 1999 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1999/02/16)

@sk

vědecký článek publikovaný v roce 1999

@cs

wetenschappelijk artikel (gepubliceerd op 1999/02/16)

@nl

наукова стаття, опублікована в лютому 1999

@uk

name

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@ast

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@en

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@nl

type

label

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@ast

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@en

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@nl

prefLabel

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@ast

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@en

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

@en

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A. Grinberg

http://www.w3.org/2001/XMLSchema#string

C. Felder

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E. Kostenis

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H. Shannon

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H. Sheng

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J. Brodkin

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J. Gomeza

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J. Wess

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L. Zhang

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P2860

Antagonist binding profiles of five cloned human muscarinic receptor subtypes

Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin

Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue

Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies

In vivo pharmacology of butylthio[2.2.2] (LY297802 / NNC11-1053), an orally acting antinociceptive muscarinic agonist.

Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic.

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice.

Muscarinic receptor subtypes.

Cholinergic mechanisms in pain and analgesia.

Muscarinic receptors--characterization, coupling and function.

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1692–1697

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scholarly article

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10.1073/PNAS.96.4.1692

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4

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96

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13299550

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9990086

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15563

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