The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
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PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.Thyroid hormone signaling in vivo requires a balance between coactivators and corepressorsDeciphering direct and indirect influence of thyroid hormone with mouse genetics.The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo.Dual functions of thyroid hormone receptors in vertebrate development: the roles of histone-modifying cofactor complexesThyroid hormone regulation of metabolismOrphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis.Transcriptional coregulators: fine-tuning metabolism.Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alphaThe interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo.Transcriptome analysis of human cancer reveals a functional role of heme oxygenase-1 in tumor cell adhesionElevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion.The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway.Mechanisms of thyroid hormone actionNuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deteriorationCrosstalk between thyroid hormone receptor and liver X receptor in the regulation of selective Alzheimer's disease indicator-1 gene expression.Alteration of NCoR corepressor splicing in mice causes increased body weight and hepatosteatosis without glucose intolerance.Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance.Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases.Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer.NCoR1 and SMRT play unique roles in thyroid hormone action in vivoUnliganded thyroid hormone receptor α controls developmental timing in Xenopus tropicalisThyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation.Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation.SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and βTissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of AgingThe nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axisThyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.Thyroid hormone receptors and resistance to thyroid hormone disorders.Thyroid hormone receptors and cancer.Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cellsPhosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice.The thyroid axis is regulated by NCoR1 via its actions in the pituitaryThe in vivo role of nuclear receptor corepressors in thyroid hormone action.Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasisThyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruption.Role of Thyroid Hormones in Skeletal Development and Bone Maintenance.Emerging roles of the corepressors NCoR1 and SMRT in homeostasis.
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P2860
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/09)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/09)
@nl
наукова стаття, опублікована в грудні 2008
@uk
name
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@ast
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@en
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@nl
type
label
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@ast
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@en
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@nl
prefLabel
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@ast
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@en
The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@nl
P2093
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P921
P3181
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The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo
@en
P2093
Anthony N. Hollenberg
Crystal Morales
Inna Astapova
Larissa J. Lee
Stefanie Tauber
P2860
P304
19544–19549
P3181
P356
10.1073/PNAS.0804604105
P407
P577
2008-12-09T00:00:00Z