Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer
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A kinase-independent role for EGF receptor in autophagy initiationResistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?Autophagy-Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin AnalogDifferential transcriptional effects of EGFR inhibitorsAutophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer.An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo.EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cellsEfficacy and mechanism of action of the tyrosine kinase inhibitors gefitinib, lapatinib and neratinib in the treatment of HER2-positive breast cancer: preclinical and clinical evidenceMacrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines.Cabazitaxel-induced autophagy via the PI3K/Akt/mTOR pathway contributes to A549 cell death.Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications.Inhibiting autophagy increases epirubicin's cytotoxicity in breast cancer cells.Concurrent Autophagy Inhibition Overcomes the Resistance of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Human Bladder Cancer Cells.PARP inhibitor reduces proliferation and increases apoptosis in breast cancer cells.EGFR inhibitors and autophagy in cancer treatment.Untangling knots between autophagic targets and candidate drugs, in cancer therapy.The potential of Beclin 1 as a therapeutic target for the treatment of breast cancer.Clinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects.Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity.Nrf2 but not autophagy inhibition is associated with the survival of wild-type epidermal growth factor receptor non-small cell lung cancer cells.Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy.Research progress of hydroxychloroquine and autophagy inhibitors on cancer.EGFR Family Members' Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer.Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer.Gefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathway.mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking.MTA1 is a novel regulator of autophagy that induces tamoxifen resistance in breast cancer cells.Copolymer micelles function as pH-responsive nanocarriers to enhance the cytotoxicity of a HER2 aptamer in HER2-positive breast cancer cells.Autophagy activation promotes bevacizumab resistance in glioblastoma by suppressing Akt/mTOR signaling pathway.Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.
P2860
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P2860
Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer
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2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Induction of autophagy is an e ...... peutic target in breast cancer
@ast
Induction of autophagy is an e ...... peutic target in breast cancer
@en
Induction of autophagy is an e ...... peutic target in breast cancer
@nl
type
label
Induction of autophagy is an e ...... peutic target in breast cancer
@ast
Induction of autophagy is an e ...... peutic target in breast cancer
@en
Induction of autophagy is an e ...... peutic target in breast cancer
@nl
prefLabel
Induction of autophagy is an e ...... peutic target in breast cancer
@ast
Induction of autophagy is an e ...... peutic target in breast cancer
@en
Induction of autophagy is an e ...... peutic target in breast cancer
@nl
P2093
P2860
P3181
P1433
P1476
Induction of autophagy is an e ...... peutic target in breast cancer
@en
P2093
Anita I Kapanen
Corinna Warburton
Elizabeth Donohue
Jenna S Rawji
Jun Chih Wang
Karen A Gelmon
Ling Yan Wong
Michel Roberge
Mohammed A Qadir
Sherry A Weppler
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0076503
P407
P577
2013-01-01T00:00:00Z