Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification - Wikidata - thesis-toulmin - TriplyDB

Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification

Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification

http://www.wikidata.org/entity/Q28565710

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Multiple Functions of MSCA-1/TNAP in Adult Mesenchymal Progenitor/Stromal Cells The role of phosphatases in the initiation of skeletal mineralization Vascular calcification: When should we interfere in chronic kidney disease patients and how?Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD.Outcome predictability of serum alkaline phosphatase in men with pre-dialysis CKD.Development of a novel chronic kidney disease mouse model to evaluate the progression of hyperphosphatemia and associated mineral bone disease Identification and characterization of novel tissue-nonspecific alkaline phosphatase inhibitors with diverse modes of action Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia The role of inorganic pyrophosphate in aortic valve calcification.Kidney bone disease and mortality in CKD: revisiting the role of vitamin D, calcimimetics, alkaline phosphatase, and minerals.Association of serum alkaline phosphatase and bone mineral density in maintenance hemodialysis patients.The appearance and modulation of osteocyte marker expression during calcification of vascular smooth muscle cells.Towards the revival of alkaline phosphatase for the management of bone disease, mortality and hip fractures.Serum alkaline phosphatase levels associate with elevated serum C-reactive protein in chronic kidney disease.Increased serum alkaline phosphatase and serum phosphate as predictors of mortality after stroke.Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure.Direct determination of phosphatase activity from physiological substrates in cells.Key role of alkaline phosphatase in the development of human-derived nanoparticles in vitro.Comparative mortality-predictability using alkaline phosphatase and parathyroid hormone in patients on peritoneal dialysis and hemodialysis.Improvement of the skeletal and dental hypophosphatasia phenotype in Alpl-/- mice by administration of soluble (non-targeted) chimeric alkaline phosphatase.Cholesterol-cholate-butterfat diet offers multi-organ dysfunction in rats.Vascular calcification is dependent on plasma levels of pyrophosphate.Plasma pyrophosphate and vascular calcification in chronic kidney disease.Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle.Matrix Gla protein metabolism in vascular smooth muscle and role in uremic vascular calcification.Associations between renal hyperfiltration and serum alkaline phosphatase.Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification.The progressive ankylosis protein regulates cementum apposition and extracellular matrix composition.Calpain-1 Mediated Disorder of Pyrophosphate Metabolism Contributes to Vascular Calcification Induced by oxLDL.Predictors of sudden cardiac death: a competing risk approach in the hemodialysis study Critical Parameters of the In Vitro Method of Vascular Smooth Muscle Cell Calcification.Osteogenic changes in kidneys of hyperoxaluric rats.Alkalosis and Dialytic Clearance of Phosphate Increases Phosphatase Activity: A Hidden Consequence of Hemodialysis.Mechanisms and clinical consequences of vascular calcification Possible association between serum alkaline phosphatase concentration and thoracicacute aortic dissection.Calpain-1 regulation of matrix metalloproteinase 2 activity in vascular smooth muscle cells facilitates age-associated aortic wall calcification and fibrosis.Impact of magnesium:calcium ratio on calcification of the aortic wall.

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Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: potential mechanism for uremic vascular calcification

http://www.wikidata.org/entity/Q28565710

description

2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2008

@ast

im Mai 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2008/05/01)

@sk

vědecký článek publikovaný v roce 2008

@cs

wetenschappelijk artikel (gepubliceerd op 2008/05/01)

@nl

наукова стаття, опублікована в травні 2008

@uk

مقالة علمية (نشرت في مايو 2008)

@ar

name

Upregulation of alkaline phosp ...... uremic vascular calcification

@ast

Upregulation of alkaline phosp ...... uremic vascular calcification

@en

Upregulation of alkaline phosp ...... uremic vascular calcification

@nl

type

label

Upregulation of alkaline phosp ...... uremic vascular calcification

@ast

Upregulation of alkaline phosp ...... uremic vascular calcification

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Upregulation of alkaline phosp ...... uremic vascular calcification

@nl

prefLabel

Upregulation of alkaline phosp ...... uremic vascular calcification

@ast

Upregulation of alkaline phosp ...... uremic vascular calcification

@en

Upregulation of alkaline phosp ...... uremic vascular calcification

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Kidney International

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Upregulation of alkaline phosp ...... uremic vascular calcification

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J L Millan

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K A Lomashvili

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S Narisawa

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W C O'Neill

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P2860

PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

Inorganic pyrophosphate generation and disposition in pathophysiology

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

Novel inhibitors of alkaline phosphatase suppress vascular smooth muscle cell calcification.

Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta, and other disorders of bone.

Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia

Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders.

The fallacy of the calcium-phosphorus product.

The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway

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10.1038/KI.2008.26

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