Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
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TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative diseaseProfile of minocycline and its potential in the treatment of schizophreniaMitochondrial calcium and the permeability transition in cell deathStabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathyATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosisCellular and Molecular Mechanisms of AKI.Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models.Suppression of microglia activation after hypoxia-ischemia results in age-dependent improvements in neurologic injury.Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke.Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells.Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.Role of microglia in a mouse model of paediatric traumatic brain injuryTargeting microglial activation in stroke therapy: pharmacological tools and gender effects.Reductions in amyloid-beta-derived neuroinflammation, with minocycline, restore cognition but do not significantly affect tau hyperphosphorylation.Minocycline chelates Ca2+, binds to membranes, and depolarizes mitochondria by formation of Ca2+-dependent ion channels.Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis.Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2.Minocycline and doxycycline, but not tetracycline, mitigate liver and kidney injury after hemorrhagic shock/resuscitationEffect of minocycline on cerebral ischemia-reperfusion injuryAutophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra.Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.Regulated cell death in AKI.Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.Minocycline protects cardiac myocytes against simulated ischemia–reperfusion injury by inhibiting poly(ADP-ribose) polymerase-1.Mitochondrial dysregulation and protection in cisplatin nephrotoxicity.Heme oxygenase-1 induction contributes to renoprotection by G-CSF during rhabdomyolysis-associated acute kidney injuryDeleterious effects of minocycline after in vivo target deprivation of thalamocortical neurons in the immature, metallothionein-deficient mouse brain.Minocycline upregulates pro-survival genes and downregulates pro-apoptotic genes in experimental glaucoma.Effects of minocycline on apoptosis and angiogenesis-related protein expression in a rat model of intracerebral hemorrhage.The benefit of minocycline on negative symptoms in early-phase psychosis in addition to standard care - extent and mechanism (BeneMin): study protocol for a randomised controlled trial.Minocycline development for acute ischemic strokePancreatic Cancer Combination Therapy Using a BH3 Mimetic and a Synthetic Tetracycline.Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trialAdjunctive Minocycline in Clozapine-Treated Schizophrenia Patients With Persistent Symptoms.Effects of Minocycline on Urine Albumin, Interleukin-6, and Osteoprotegerin in Patients with Diabetic Nephropathy: A Randomized Controlled Pilot Trial.Minocycline decreases liver injury after hemorrhagic shock and resuscitation in miceMechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation.Minocycline as a neuroprotective agent.Minocycline for short-term neuroprotectionMouse model of ischemic acute kidney injury: technical notes and tricks
P2860
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P2860
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
description
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Mai 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/05/07)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/05/07)
@nl
наукова стаття, опублікована в травні 2004
@uk
name
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@ast
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@en
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@nl
type
label
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@ast
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@en
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@nl
prefLabel
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@ast
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@en
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@nl
P2093
P2860
P3181
P356
P1476
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria
@en
P2093
Cong-Yi Wang
David C. Hess
Jinzhao Wang
Qingqing Wei
William D. Hill
Zheng Dong
P2860
P304
19948–19954
P3181
P356
10.1074/JBC.M313629200
P407
P577
2004-05-07T00:00:00Z