Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
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Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formationAntidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in ratsSerotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disordersPharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunumCharacterization of [(125)I]-SB-258585 binding to human recombinant and native 5-HT(6) receptors in rat, pig and human brain tissueFurther evidence that 5-HT-induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT(2B) receptorsIn vivo effects of the 5-HT(6) antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate5-HT6 receptors and Alzheimer's diseaseInflammation and Alzheimer's diseaseValerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitroStudy of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's diseaseThe 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variantsAVN-101: A Multi-Target Drug Candidate for the Treatment of CNS Disorders.Molecular targets for treating cognitive dysfunction in schizophrenia.Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition.5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine.Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent ProtocolThe 5-HT7 receptor and disorders of the nervous system: an overview.Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors.5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.Pharmacotherapy of sexual dysfunctions : current status.Selective serotonin reuptake inhibitors: a review of its effects on intraocular pressureEnhancement of cyclic AMP accumulation mediated by 5-HT after chronic amitriptyline treatment in NG 108-15 cells.Alzheimer's disease and age-related memory decline (preclinical)Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonistIncreased expression of 5-HT₆ receptors in dorsolateral striatum decreases habitual lever pressing, but does not affect learning acquisition of simple operant tasks in rats.Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptorsInvestigation of the structure requirement for 5-HT₆ binding affinity of arylsulfonyl derivatives: a computational studyThe 5-HT(7) receptor in learning and memory.Characterization of putative 5-ht7 receptors mediating direct relaxation in Cynomolgus monkey isolated jugular vein.The relaxant 5-HT receptor in the dog coronary artery smooth muscle: pharmacological resemblance to the cloned 5-ht7 receptor subtype.Pharmacological characterization of the 5-hydroxytryptamine receptor mediating relaxation in the rat isolated ileum5-HT(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms.Clozapine: selective labeling of sites resembling 5HT6 serotonin receptors may reflect psychoactive profile.Activation of 5-HT6 receptors modulates sleep-wake activity and hippocampal theta oscillationAssessing the neuronal serotonergic target-based antidepressant stratagem: impact of in vivo interaction studies and knockout modelsThe serotonin-6 receptor as a novel therapeutic target.Serotonin mediation of early memory formation via 5-HT2B receptor-induced glycogenolysis in the day-old chick.
P2860
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P2860
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
description
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im März 1993 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1993/03/01)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/03/01)
@nl
наукова стаття, опублікована в березні 1993
@uk
مقالة علمية (نشرت في مارس 1993)
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name
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@ast
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@en
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@nl
type
label
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@ast
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@en
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@nl
prefLabel
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@ast
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@en
Cloning and expression of a no ...... r tricyclic psychotropic drugs
@nl
P2093
P3181
P1476
Cloning and expression of a no ...... r tricyclic psychotropic drugs
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P2093
P304
P3181
P577
1993-03-01T00:00:00Z