Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload
about
Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contendersLack of Plasma Protein Hemopexin Results in Increased Duodenal Iron UptakeHaptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug developmentAtherogenesis and iron: from epidemiology to cellular level.Heme degradation and vascular injury.Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity.A role for hemopexin in oligodendrocyte differentiation and myelin formation.Hemolysis-induced lethality involves inflammasome activation by hemePlacental heme receptor LRP1 correlates with the heme exporter FLVCR1 and neonatal iron statusDysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution.Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice.Control of intracellular heme levels: heme transporters and heme oxygenasesExcess of heme induces tissue factor-dependent activation of coagulation in mice.Red Blood Cells Preconditioned with Hemin Are Less Permissive to Plasmodium Invasion In Vivo and In VitroHeme-Mediated Induction of CXCL10 and Depletion of CD34+ Progenitor Cells Is Toll-Like Receptor 4 DependentMultifaceted Role of Heme during Severe Plasmodium falciparum Infections in IndiaOne ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoansHemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles.Data demonstrating the anti-oxidant role of hemopexin in the heart.Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteinsApolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function.Diabetes augments and inhaled nitric oxide prevents the adverse hemodynamic effects of transfusing syngeneic stored blood in mice.Extracellular hemin crisis triggers acute chest syndrome in sickle miceHepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease.Trafficking of heme and porphyrins in metazoa.CD163 and inflammation: biological, diagnostic, and therapeutic aspects.Therapeutic approaches to limit hemolysis-driven endothelial dysfunction: scavenging free heme to preserve vasculature homeostasis.Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes.Heme on innate immunity and inflammation.New perspectives on the thrombotic complications of haemolysis.Heme Mobilization in Animals: A Metallolipid's Journey.Dynamic interactions of Plasmodium spp. with vascular endothelium.Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease.Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.Heme as a Target for Therapeutic Interventions.Iron transport proteins: Gateways of cellular and systemic iron homeostasis.Heme-hemopexin complex attenuates neuronal cell death and stroke damage.Endothelial dysfunction inhibits the ability of haptoglobin to prevent hemoglobin-induced hypertension.Haemopexin affects iron distribution and ferritin expression in mouse brain.Expression of ABCG2 (BCRP) in mouse models with enhanced erythropoiesis.
P2860
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P2860
Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload
description
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Juni 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/07/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/07/01)
@nl
наукова стаття, опублікована в липні 2008
@uk
مقالة علمية (نشرت في يوليو 2008)
@ar
name
Hemopexin prevents endothelial ...... a mouse model of heme overload
@ast
Hemopexin prevents endothelial ...... a mouse model of heme overload
@en
Hemopexin prevents endothelial ...... a mouse model of heme overload
@nl
type
label
Hemopexin prevents endothelial ...... a mouse model of heme overload
@ast
Hemopexin prevents endothelial ...... a mouse model of heme overload
@en
Hemopexin prevents endothelial ...... a mouse model of heme overload
@nl
prefLabel
Hemopexin prevents endothelial ...... a mouse model of heme overload
@ast
Hemopexin prevents endothelial ...... a mouse model of heme overload
@en
Hemopexin prevents endothelial ...... a mouse model of heme overload
@nl
P2093
P2860
P1476
Hemopexin prevents endothelial ...... a mouse model of heme overload
@en
P2093
Fiorella Altruda
Lorenzo Silengo
Stefania Gastaldi
P2860
P304
P356
10.2353/AJPATH.2008.071130
P407
P577
2008-06-13T00:00:00Z