The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
about
Nuclear Localization of Suppressor of Cytokine Signaling-1 Regulates Local Immunity in the Lung.A hypothalamic circuit that controls body temperature.Feeling Hot and Cold: Thermal Sensation in Drosophila.TRP channels in oxygen physiology: distinctive functional properties and roles of TRPA1 in O2 sensing.The TRPM2 channel: A thermo-sensitive metabolic sensor.3-Iodothyronamine, a Novel Endogenous Modulator of Transient Receptor Potential Melastatin 8?The TRPM2 channel in temperature detection and thermoregulation.Deconstructing mammalian thermoregulation.Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells.Warm feelings for TRPM2.Evidence of viscerally-mediated cold-defence thermoeffector responses in man.Different Principles of ADP-Ribose-Mediated Activation and Opposite Roles of the NUDT9 Homology Domain in the TRPM2 Orthologs of Man and Sea Anemone.2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist.Thermoregulatory inversion: a novel thermoregulatory paradigm.Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity.Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism.Sensing the heat with TRPM3.The Hypothalamic Preoptic Area and Body Weight Control.A strong and flexible electronic vessel for real-time monitoring of temperature, motions and flow.Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential.Central regulation of brown adipose tissue thermogenesis and energy homeostasis dependent on food availability.Changes in thermoregulation and monoamine release in freely moving rats during cold exposure and inhibition of the ventromedial, dorsomedial, or posterior hypothalamus.Selective inhibition of TRPM2 channel by two novel synthesized ADPR analogues.Nociceptive Roles of TRPM2 Ion Channel in Pathologic Pain.Targeting nociceptive transient receptor potential channels to treat chronic pain: current state of the field.Ca2+ Regulation of TRP Ion Channels.TRPM2: a candidate therapeutic target for treating neurological diseases.Regulation of Body Temperature by the Nervous System.TRPM2 and warmth sensation.Neural control of parental behaviors.Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.Identification of a Novel EF-Loop in the N-terminus of TRPM2 Channel Involved in Calcium Sensitivity.TRPM2 in the Brain: Role in Health and Disease3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell LinesBrs3 neurons in the mouse dorsomedial hypothalamus regulate body temperature, energy expenditure, and heart rate, but not food intakeThe neural circuits of thermal perception
P2860
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P2860
The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
description
2016 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2016
@ast
im September 2016 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2016/09/23)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/09/23)
@nl
наукова стаття, опублікована у вересні 2016
@uk
name
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@ast
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@en
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@nl
type
label
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@ast
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@en
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@nl
prefLabel
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@ast
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@en
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@nl
P2093
P2860
P356
P1433
P1476
The TRPM2 channel is a hypotha ...... ever and can drive hypothermia
@en
P2093
Fernanda de Castro Reis
Gretel B Kamm
Jan Siemens
Jörg Pohle
Paul Heppenstall
P2860
P304
P356
10.1126/SCIENCE.AAF7537
P407
P50
P577
2016-08-25T00:00:00Z