Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3
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The aorta and heart differentially express RGS (regulators of G-protein signalling) proteins that selectively regulate sphingosine 1-phosphate, angiotensin II and endothelin-1 signallingLysophospholipids and their receptors in the central nervous systemLipid phosphate phosphatase (LPP3) and vascular developmentFingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapySperm Associated Antigen 6 (SPAG6) Regulates Fibroblast Cell Growth, Morphology, Migration and Ciliogenesis.Lysophospholipid receptors in drug discovery.In vitro and in vivo antagonism of a G protein-coupled receptor (S1P3) with a novel blocking monoclonal antibodyMurine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expressionSphingosine 1-phosphate chemical biologyInternational Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNSRole of LPA4/p2y9/GPR23 in negative regulation of cell motilityBiological roles of lysophospholipid receptors revealed by genetic null mice: an update.Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.Ablation of Sphingosine 1-Phosphate Receptor Subtype 3 Impairs Hippocampal Neuron Excitability In vitro and Spatial Working Memory In vivoNovel GPCR screening approach: indirect identification of S1P receptor agonists in antagonist screening using a calcium assay.S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cellsCharacterization and Expression of Sphingosine 1-Phosphate Receptors in Human and Rat Heart.Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes.The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient.Lysophospholipid receptor nomenclature review: IUPHAR Review 8.Sphingosine 1-phosphate, a key cell signaling molecule.Extracellular and intracellular actions of sphingosine-1-phosphateCharacterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing.Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury."Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets.Sphingosine-1 phosphate receptor (S1p1), a critical receptor controlling human lymphocyte trafficking, is expressed in hen and human ovaries and ovarian tumors.Unique uterine localization and regulation may differentiate LPA3 from other lysophospholipid receptors for its role in embryo implantation.Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist.Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites.Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.Sphingosine-1-phosphate receptor 2The impact of bioactive lipids on cardiovascular development.
P2860
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P2860
Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3
description
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im September 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/09/07)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/09/07)
@nl
наукова стаття, опублікована у вересні 2001
@uk
name
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@ast
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@en
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@nl
type
label
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@ast
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@en
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@nl
prefLabel
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@ast
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@en
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@nl
P2093
P2860
P921
P3181
P356
P1476
Selective loss of sphingosine ...... coupled receptor, LP(B3)/EDG-3
@en
P2093
B. Friedman
C. McGiffert
J. H. Brown
J. J. Contos
M. A. Kingsbury
S. Kawamura
P2860
P304
33697–33704
P3181
P356
10.1074/JBC.M104441200
P407
P577
2001-09-07T00:00:00Z