TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
about
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosisMutations in PAX2 associate with adult-onset FSGSSNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activityPositional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversibleCOQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyTRPC6 in glomerular health and disease: what we know and what we believeLarge-Conductance Calcium-Activated Potassium Channels in Glomerulus: From Cell Signal Integration to DiseasePodocytesCalcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapiesNonimmunologic targets of immunosuppressive agents in podocytesWnt/β-catenin signaling and kidney fibrosisGenetic causes of focal segmental glomerulosclerosis: implications for clinical practiceThe renal channelopathiesCell biology and pathology of podocytesThe function of endocytosis in podocytesThe Impact of Histologic Variants on FSGS OutcomesNovel siRNA delivery system to target podocytes in vivoCalcium regulates podocyte actin dynamics.TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseasesTransient receptor potential channels as therapeutic targetsPodocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndromeNOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complexEstablishment of protein delivery systems targeting podocytesp53 increases intra-cellular calcium release by transcriptional regulation of calcium channel TRPC6 in GaQ3-treated cancer cellsCanonical transient receptor potential 6 (TRPC6), a redox-regulated cation channelMice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activityTRP channelsPodocyte glutamatergic signaling contributes to the function of the glomerular filtration barrier.Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone.Inducible podocyte injury and proteinuria in transgenic zebrafish.Intravital imaging of podocyte calcium in glomerular injury and disease.Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli.A novel TRPC6 mutation that causes childhood FSGS.New perspectives on the renal slit diaphragm protein podocin.NPHS2 variation in focal and segmental glomerulosclerosis.DGKE and atypical HUS.Ligation of alpha-dystroglycan on podocytes induces intracellular signaling: a new mechanism for podocyte effacement?Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAsSubfractionation, characterization, and in-depth proteomic analysis of glomerular membrane vesicles in human urine
P2860
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P2860
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
description
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2005
@ast
im Juli 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/07/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/07/01)
@nl
наукова стаття, опублікована в липні 2005
@uk
name
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@ast
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@en
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@nl
type
label
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@ast
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@en
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@nl
prefLabel
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@ast
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@en
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
TRPC6 is a glomerular slit dia ...... ired for normal renal function
@en
P2093
Carmen Avila-Casado
Changli Wei
Christian Faul
Clemens C. Möller
Dennis Brown
Hikaru Sugimoto
Ivan Villegas
Jochen Reiser
Krishna R. Polu
Martin R. Pollak
P2860
P2888
P304
P3181
P356
10.1038/NG1592
P407
P577
2005-07-01T00:00:00Z