High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region
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Human antibody production in transgenic animalsHumanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire.Generation and analysis of the improved human HAL9/10 antibody phage display libraries.Selection of Recombinant Human Antibodies.Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies.Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells.Expression of recombinant antibodies.Advances in transgenic animal models and techniques.Advances in genetic engineering of the avian genome: "Realising the promise".Discovery and bio-optimization of human antibody therapeutics using the XenoMouse® transgenic mouse platform.Designing Human Antibodies by Phage DisplayComplete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation.Functionally Convergent B Cell Receptor Sequences in Transgenic Rats Expressing a Human B Cell Repertoire in Response to Tetanus Toxoid and Measles Antigens.A novel one-step approach for the construction of yeast surface display Fab antibody libraries.Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs.Generation of human bispecific common light chain antibodies by combining animal immunization and yeast display.Sex-, stress-, and sympathetic post-ganglionic-dependent changes in identity and proportions of immune cells in the dura.Transgenic animals and genetic engineering techniques. Nantes, France, 2-3 July, 2015.Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies.Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.Evolution of Therapeutic Antibodies, Influenza Virus Biology, Influenza, and Influenza Immunotherapy.Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries
P2860
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P2860
High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@ast
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@en
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@nl
type
label
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@ast
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@en
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@nl
prefLabel
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@ast
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@en
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@nl
P2093
P2860
P356
P1476
High-affinity IgG antibodies d ...... loci bearing the rat CH region
@en
P2093
Anne-Laure Iscache
Arvind Rajpal
Ashleigh Binnie
Ignacio Anegon
Jeanette Dilley
Kevin Lindquist
Laure-Hélène Ouisse
Marianne Brüggemann
Michael J Osborn
P2860
P304
P356
10.4049/JIMMUNOL.1203041
P407
P577
2013-02-15T00:00:00Z