Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice
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Metabolic benefits of resistance training and fast glycolytic skeletal muscle.Effect of myostatin depletion on weight gain, hyperglycemia, and hepatic steatosis during five months of high-fat feeding in micePlasma and muscle myostatin in relation to type 2 diabetes.METABOLIC FUNCTIONS OF MYOSTATIN AND GDF11.Increased energy expenditure and leptin sensitivity account for low fat mass in myostatin-deficient mice.Synergistic and antagonistic interplay between myostatin gene expression and physical activity levels on gene expression patterns in triceps Brachii muscles of C57/BL6 mice.Expression and function of myostatin in obesity, diabetes, and exercise adaptation.Soluble activin receptor type IIB treatment does not cause fat loss in mice with diet-induced obesity.Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activityBlockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolismMyostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.Mammalian Mss51 is a skeletal muscle-specific gene modulating cellular metabolism.Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old miceInhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues.Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle.Sarcopenic obesity and endocrinal adaptation with ageIncreasing muscle mass to improve metabolism.Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.Inhibition of in vitro and in vivo brown fat differentiation program by myostatin.Astragalus polysaccharide suppresses skeletal muscle myostatin expression in diabetes: involvement of ROS-ERK and NF-κB pathways.Molecular pathways regulating the formation of brown-like adipocytes in white adipose tissue.A new, highly selective murine peroxisome proliferator-activated receptor δ agonist increases responsiveness to thermogenic stimuli and glucose uptake in skeletal muscle in obese mice.Myostatin and its association with abdominal obesity, androgen and follistatin levels in women with polycystic ovary syndrome.Transcript characteristic of myostatin in sheep fibroblasts.The correlation of resistance exercise-induced myostatin with insulin resistance and plasma cytokines in healthy young men.Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice.Building muscle, browning fat and preventing obesity by inhibiting myostatin.Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.Modulation of transforming growth factor-β/follistatin signaling and white adipose browning: therapeutic implications for obesity related disorders.Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin-blocked mdx mice.Myostatin knockout induces apoptosis in human cervical cancer cells via elevated reactive oxygen species generation
P2860
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P2860
Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@ast
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@en
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@nl
type
label
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@ast
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@en
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@nl
prefLabel
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@ast
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@en
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@nl
P2093
P2860
P1433
P1476
Postnatal PPARdelta activation ...... f obese insulin-resistant mice
@en
P2093
Alan C Opsahl
Barbara L Bernardo
John R Hadcock
Kyle M Judkins
Patricia G Cosgrove
Thomas B Freeman
Timothy S Wachtmann
P2860
P304
P356
10.1371/JOURNAL.PONE.0011307
P407
P577
2010-06-25T00:00:00Z