RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance
about
Unwinding and rewinding: double faces of helicase?The role of RecQ helicases in non-homologous end-joiningRECQL4 in genomic instability and agingRoles of DNA helicases in the maintenance of genome integrityYeast Pif1 accelerates annealing of complementary DNA strands.Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityCell biology of disease: Telomeropathies: an emerging spectrum disorderRecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cellsHuman RECQL1 participates in telomere maintenanceSenescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice.Human CST promotes telomere duplex replication and general replication restart after fork stalling.The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres."...Rewritten in the skin": clues to skin biology and aging from inherited disease.RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrityDNA helicases associated with genetic instability, cancer, and aging.Human RecQ helicases in DNA repair, recombination, and replication.The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability.Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells.Rothmund-Thomson Syndrome: novel pathogenic mutations and frequencies of variants in the RECQL4 and USB1 (C16orf57) gene.The RECQL4 protein, deficient in Rothmund-Thomson syndrome is active on telomeric D-loops containing DNA metabolism blocking lesionsPosttranslational control of telomere maintenance and the telomere damage response.DNA Damage, DNA Repair, Aging, and NeurodegenerationSolving the Telomere Replication Problem.DNA Replication Origins and Fork Progression at Mammalian TelomeresTargeted cargo delivery in senescent cells using capped mesoporous silica nanoparticles.Yeast Hrq1 shares structural and functional homology with the disease-linked human RecQ4 helicase.Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome.Hrq1 functions independently of Sgs1 to preserve genome integrity in Saccharomyces cerevisiae.RECQL4 Regulates p53 Function In Vivo During Skeletogenesis.Ribosomal Protein S3 Negatively Regulates Unwinding Activity of RecQ-like Helicase 4 through Their Physical Interaction.Rothmund-Thomson Syndrome: Insights from New Patients on the Genetic Variability Underpinning Clinical Presentation and Cancer Outcome.Fabrication of Aromatic Polyimide Membrane to Study the Pervaporative Separation of Phenanthrene/n-tetradecane Mixtures (Model Diesel) and Process Optimization Using Response Surface MethodologyThe Hrq1 and Pif1 DNA helicases synergistically modulate telomerase activityRecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity
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P2860
RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance
description
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2012
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scientific journal article
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wetenschappelijk artikel (gepubliceerd op 2012/01/02)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в січні 2012
@uk
مقالة علمية (نشرت في 2-1-2012)
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name
RECQL4, the protein mutated in ...... ctions in telomere maintenance
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RECQL4, the protein mutated in ...... ctions in telomere maintenance
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RECQL4, the protein mutated in ...... ctions in telomere maintenance
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RECQL4, the protein mutated in ...... ctions in telomere maintenance
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RECQL4, the protein mutated in ...... ctions in telomere maintenance
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RECQL4, the protein mutated in ...... ctions in telomere maintenance
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P2093
P2860
P921
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RECQL4, the protein mutated in ...... ctions in telomere maintenance
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P2093
Avik K Ghosh
Christopher Dunn
Deborah L Croteau
Dharmendra Kumar Singh
Marie L Rossi
Vilhelm A Bohr
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P304
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10.1074/JBC.M111.295063
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P577
2011-10-28T00:00:00Z