C/EBP and DEK coordinately regulate myeloid differentiation - Wikidata - thesis-toulmin - TriplyDB

C/EBP and DEK coordinately regulate myeloid differentiation

C/EBP and DEK coordinately regulate myeloid differentiation

http://www.wikidata.org/entity/Q29041284

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Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.Intercellular trafficking of the nuclear oncoprotein DEK.The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers Granulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells.Proteomic analysis demonstrates activator- and chromatin-specific recruitment to promoters.DEK protein level is a biomarker of CD138positive normal and malignant plasma cells.Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).C/EBPα regulates osteoclast lineage commitment The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners.Chromatin redistribution of the DEK oncoprotein represses hTERT transcription in leukemias DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis.Molecular mechanisms of curcumin action: gene expression.Concise review: role of DEK in stem/progenitor cell biology IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival.C/EBPα in normal and malignant myelopoiesis.The DEK oncoprotein and its emerging roles in gene regulation.Leucine-rich repeat kinase 2 and Parkinson's disease.Affinity purification strategies for proteomic analysis of transcription factor complexes.A role for intracellular and extracellular DEK in regulating hematopoiesis.DEK over-expression promotes mitotic defects and micronucleus formation.Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.Transcription factor CCAAT/enhancer-binding protein-β upregulates microRNA, let-7f-1 in human endocervical cells.

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C/EBP and DEK coordinately regulate myeloid differentiation

http://www.wikidata.org/entity/Q29041284

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

C/EBP and DEK coordinately regulate myeloid differentiation

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C/EBP and DEK coordinately regulate myeloid differentiation

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type

label

C/EBP and DEK coordinately regulate myeloid differentiation

@ast

C/EBP and DEK coordinately regulate myeloid differentiation

@en

prefLabel

C/EBP and DEK coordinately regulate myeloid differentiation

@ast

C/EBP and DEK coordinately regulate myeloid differentiation

@en

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BLOOD-2011-10-383083

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C/EBPα and DEK coordinately regulate myeloid differentiation

@en

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C John Luckey

http://www.w3.org/2001/XMLSchema#string

Guido Marcucci

http://www.w3.org/2001/XMLSchema#string

Hanna S Radomska

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Jarrod A Marto

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John A Alberta

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Marlene J Carrasco-Alfonso

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Rositsa I Koleva

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Scott B Ficarro

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P2860

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size

The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest

In prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damage

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

Transcriptional activation by AP-2alpha is modulated by the oncogene DEK

The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

Chromatin immunoprecipitation (ChIP) studies indicate a role for CCAAT enhancer binding proteins alpha and epsilon (C/EBP alpha and C/EBP epsilon ) and CDP/cut in myeloid maturation-induced lactoferrin gene expression

Identification of a co-repressor that inhibits the transcriptional and growth-arrest activities of CCAAT/enhancer-binding protein alpha

C/EBPalpha deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo

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4878-4888

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scholarly article

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10.1182/BLOOD-2011-10-383083

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P433

21

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119

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James T. Webber

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2012-04-03T00:00:00Z

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223986706

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22474248

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3367892

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