Tau suppression in a neurodegenerative mouse model improves memory function - Wikidata - thesis-toulmin - TriplyDB

Tau suppression in a neurodegenerative mouse model improves memory function

Tau suppression in a neurodegenerative mouse model improves memory function

http://www.wikidata.org/entity/Q29615831

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Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease Oxidative Stress Signaling in Alzheimers Disease Actin-binding proteins coronin-1a and IBA-1 are effective microglial markers for immunohistochemistry LRRK2 phosphorylates novel tau epitopes and promotes tauopathy Hsp90-Tau complex reveals molecular basis for specificity in chaperone action Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1 Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study Synapses and Alzheimer's disease Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration Glial Tau Pathology in Tauopathies: Functional Consequences Imaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence Imaging The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost Tau Oligomers: The Toxic Player at Synapses in Alzheimer's Disease Chaperones in Neurodegeneration Protective effects and mechanisms of sirtuins in the nervous system Diverse molecular targets for therapeutic strategies in Alzheimer's disease Mouse models of frontotemporal dementia Alzheimer's therapeutics: translation of preclinical science to clinical drug development Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Breaking the Code of Amyloid-β Oligomers Mechanisms of protein seeding in neurodegenerative diseases Therapeutic and diagnostic challenges for frontotemporal dementia Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing Problem The role of tau in neurodegenerative diseases and its potential as a therapeutic target Tau and tauopathies Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy Rescue from tau-induced neuronal dysfunction produces insoluble tau oligomers Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models Depletion of microglia and inhibition of exosome synthesis halt tau propagation.Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD.Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes Characterization of inducible models of Tay-Sachs and related disease 3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.

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Tau suppression in a neurodegenerative mouse model improves memory function

http://www.wikidata.org/entity/Q29615831

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Tau suppression in a neurodegenerative mouse model improves memory function

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Tau suppression in a neurodegenerative mouse model improves memory function

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type

label

Tau suppression in a neurodegenerative mouse model improves memory function

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Tau suppression in a neurodegenerative mouse model improves memory function

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prefLabel

Tau suppression in a neurodegenerative mouse model improves memory function

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Tau suppression in a neurodegenerative mouse model improves memory function

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Tau suppression in a neurodegenerative mouse model improves memory function

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Ashe KH

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DeTure M

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Forster C

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Guimaraes A

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Hutton M

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Hyman B

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Ingelsson M

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Janus C

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Kotilinek L

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Kuskowski M

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P2860

A protein factor essential for microtubule assembly

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

Control of memory formation through regulated expression of a CaMKII transgene

Tau filament formation in transgenic mice expressing P301L tau.

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neurodegeneration

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