mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
about
Guidelines for the use and interpretation of assays for monitoring autophagyGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal functionMetabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic stateSH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signalingGlucocerebrosidase is shaking up the synucleinopathiesThe effects of testosterone deprivation and supplementation on proteasomal and autophagy activity in the skeletal muscle of the male mouse: differential effects on high-androgen responder and low-androgen responder muscle groupsRegulation of TOR by small GTPasesThe cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunctionmTOR signaling in growth control and diseaseThe role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistanceCryo-EM studies of the structure and dynamics of vacuolar-type ATPasesConserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingThe Emerging Role of Branched-Chain Amino Acids in Insulin Resistance and MetabolismAmino Acid Sensing by mTORC1: Intracellular Transporters Mark the SpotAdvances in Autophagy Regulatory MechanismsThe crucial impact of lysosomes in aging and longevityRegulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glanceAmino acid management in cancerThe neurology of mTORThe molecular basis for load-induced skeletal muscle hypertrophyAutophagy and the (Pro)renin ReceptorThe role of TRPMLs in endolysosomal trafficking and functionmTOR-dependent cell survival mechanismsRegulatory cells and transplantation toleranceSkeletal muscle autophagy: a new metabolic regulatorRole of amino acid transporters in amino acid sensingAmino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOREmerging strategies to effectively target autophagy in cancerAmino acids and mTORC1: from lysosomes to diseaseMultifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscleIntegration of signals generated by nutrients, hormones, and exercise in skeletal muscleAutophagy modulation as a potential therapeutic target for diverse diseasesβA3/A1-crystallin: more than a lens proteinPhosphoinositides: tiny lipids with giant impact on cell regulation
P2860
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P2860
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@ast
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@en
type
label
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@ast
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@en
prefLabel
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@ast
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@en
P2093
P2860
P3181
P356
P1433
P1476
mTORC1 senses lysosomal amino ...... uires the vacuolar H(+)-ATPase
@en
P2093
Liron Bar-Peled
Roberto Zoncu
Shuyu Wang
Yasemin Sancak
P2860
P304
P3181
P356
10.1126/SCIENCE.1207056
P407
P577
2011-11-01T00:00:00Z