HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
about
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodiesAncient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3GThe dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3GFAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cellsRestriction of foamy viruses by APOBEC cytidine deaminasesTRIM5α and Species Tropism of HIV/SIVAPOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradationMutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificitiesDifferential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion.Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylasesRole and mechanism of action of the APOBEC3 family of antiretroviral resistance factorsDifferential requirement for conserved tryptophans in human immunodeficiency virus type 1 Vif for the selective suppression of APOBEC3G and APOBEC3F.The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activitiesHuman APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replicationHIV-1 Vif and APOBEC3G: multiple roads to one goalA second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteinsTargeting APOBEC3A to the viral nucleoprotein complex confers antiviral activityA single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletionDifferential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypesStructural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3GHIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factorsPrototype foamy virus Bet impairs the dimerization and cytosolic solubility of human APOBEC3GHIV-1 Vif, APOBEC, and intrinsic immunityStructure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3GAPOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replicationAlternative induction of meiotic recombination from single-base lesions of DNA deaminasesHuman cytidine deaminase APOBEC3H restricts HIV-1 replicationA single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivityCytidine deamination induced HIV-1 drug resistanceThe HIV-1 Vif PPLP motif is necessary for human APOBEC3G binding and degradationStructural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assemblyIdentification of APOBEC3DE as another antiretroviral factor from the human APOBEC familyDDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrestIdentification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidationInduction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3GEarly steps of retrovirus replicative cycle
P2860
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P2860
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@ast
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@en
type
label
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@ast
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@en
prefLabel
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@ast
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@en
P2093
P3181
P356
P1433
P1476
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
@en
P2093
P2888
P304
P3181
P356
10.1038/NM946
P407
P577
2003-11-01T00:00:00Z
P6179
1040253375