c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential. - Wikidata - thesis-toulmin - TriplyDB

c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.

c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.

http://www.wikidata.org/entity/Q30157161

about

Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers Targeting Src family kinases in anti-cancer therapies: turning promise into triumph Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk.Spatiotemporal regulation of Src and its substrates at invadosomes Polarized endocytosis of the keratinocyte growth factor receptor in migrating cells: role of SRC-signaling and cortactin Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways Interferon tau regulates PGF2alpha release from the ovine endometrial epithelial cells via activation of novel JAK/EGFR/ERK/EGR-1 pathways.Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth Oncogenes and tumor suppressor genes Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer.A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment.Protein kinase Cδ is required for ErbB2-driven mammary gland tumorigenesis and negatively correlates with prognosis in human breast cancer.Adaptive responses to dasatinib-treated lung squamous cell cancer cells harboring DDR2 mutations.Lung cancer and lung injury: the dual role of ceramide Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells Cigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.Src regulates Tyr(20) phosphorylation of transferrin receptor-1 and potentiates breast cancer cell survival Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis.EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function Epidermal growth factor-stimulated Akt phosphorylation requires clathrin or ErbB2 but not receptor endocytosis Development of a 5-plex SILAC method tuned for the quantitation of tyrosine phosphorylation dynamics.Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes ErbB2, FoxM1 and 14-3-3ζ prime breast cancer cells for invasion in response to ionizing radiation.Multidrug therapy for polycystic kidney disease: a review and perspective.Dasatinib inhibits mammary tumour development in a genetically engineered mouse model.KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.Src kinase mediates productive endocytic sorting of reovirus during cell entry.Similar requirement for clathrin in EGF- and HGF- stimulated Akt phosphorylation.

P2860

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P2860

c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.

http://www.wikidata.org/entity/Q30157161

description

2009 nî lūn-bûn

@nan

2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

c-Src associates with ErbB2 th ...... hanced transforming potential.

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c-Src associates with ErbB2 th ...... hanced transforming potential.

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type

label

c-Src associates with ErbB2 th ...... hanced transforming potential.

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c-Src associates with ErbB2 th ...... hanced transforming potential.

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prefLabel

c-Src associates with ErbB2 th ...... hanced transforming potential.

@ast

c-Src associates with ErbB2 th ...... hanced transforming potential.

@en

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P356

P1433

Molecular and Cellular Biology

P1476

c-Src associates with ErbB2 th ...... hanced transforming potential.

@en

P2093

Calvin D Roskelly

http://www.w3.org/2001/XMLSchema#string

Harold Kim

http://www.w3.org/2001/XMLSchema#string

Lixin Zhou

http://www.w3.org/2001/XMLSchema#string

Richard Marcotte

http://www.w3.org/2001/XMLSchema#string

William J Muller

http://www.w3.org/2001/XMLSchema#string

P2860

Newest findings on the oldest oncogene; how activated src does it

pp60c-src activation in human colon carcinoma

Activation and association of Stat3 with Src in v-Src-transformed cell lines

A new model for ductal carcinoma in situ suggests strategies for treatment

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

Docking interactions in protein kinase and phosphatase networks

Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor

Epidermal growth factor receptor mutations in lung cancer

The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation.

P304

5858-5871

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scholarly article

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10.1128/MCB.01731-08

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21

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29

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2009-08-24T00:00:00Z

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19704002

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2772728

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