Site-directed tryptophan fluorescence reveals the solution structure of tear lipocalin: evidence for features that confer promiscuity in ligand binding.
about
Lacritin and the tear proteome as natural replacement therapy for dry eyeThe 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligandsExcited protein states of human tear lipocalin for low- and high-affinity ligand binding revealed by functional AB loop motion.Probing tertiary structure of proteins using single Trp mutations with circular dichroism at low temperature.Restoration of structural stability and ligand binding after removal of the conserved disulfide bond in tear lipocalin.Exploring protein solution structure: Second moments of fluorescent spectra report heterogeneity of tryptophan rotamers.Tryptophan rotamer distribution revealed for the α-helix in tear lipocalin by site-directed tryptophan fluorescenceOligomeric state of lipocalin-1 (LCN1) by multiangle laser light scattering and fluorescence anisotropy decay.Tear lipocalin captures exogenous lipid from abnormal corneal surfaces.Effect of short- and long-range interactions on trp rotamer populations determined by site-directed tryptophan fluorescence of tear lipocalinSite-directed circular dichroism of proteins: 1Lb bands of Trp resolve position-specific features in tear lipocalinAntibacterial activity of rifamycins for M. smegmatis with comparison of oxidation and binding to tear lipocalin.Tear film lipids.Tear lipocalin: evidence for a scavenging function to remove lipids from the human corneal surface.Ligand binding site of tear lipocalin: contribution of a trigonal cluster of charged residues probed by 8-anilino-1-naphthalenesulfonic acid.Characterization of fluorescence of ANS-tear lipocalin complex: evidence for multiple-binding modes.Double tryptophan exciton probe to gauge proximal side chains in proteins: augmentation at low temperature.Molten globule state of tear lipocalin: ANS binding restores tertiary interactions.pH-Dependent conformational changes in tear lipocalin by site-directed tryptophan fluorescenceTear lipocalin is the major endonuclease in tears.The conserved disulfide bond of human tear lipocalin modulates conformation and lipid binding in a ligand selective manner.Cation-π interactions in lipocalins: structural and functional implications.Evidence for internal and external binding sites on human tear lipocalin.Intracavitary ligand distribution in tear lipocalin by site-directed tryptophan fluorescence.Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis.EF loop conformational change triggers ligand binding in beta-lactoglobulins.Interaction of ceramides and tear lipocalin.The first UV absorption band of l-tryptophan is not due to two simultaneous orthogonal electronic transitions differing in the dipole moment.
P2860
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P2860
Site-directed tryptophan fluorescence reveals the solution structure of tear lipocalin: evidence for features that confer promiscuity in ligand binding.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@ast
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@en
type
label
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@ast
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@en
prefLabel
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@ast
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@en
P2093
P356
P1433
P1476
Site-directed tryptophan fluor ...... promiscuity in ligand binding.
@en
P2093
Abduragimov AR
Gasymov OK
Glasgow BJ
Yusifov TN
P304
14754-14762
P356
10.1021/BI0110342
P407
P577
2001-12-01T00:00:00Z