Meiotic recombination favors the spreading of deleterious mutations in human populations.
about
Evidence for hitchhiking of deleterious mutations within the human genome.Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive allelesLess is more in mammalian phylogenomics: AT-rich genes minimize tree conflicts and unravel the root of placental mammals.A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes.Biased gene conversion and GC-content evolution in the coding sequences of reptiles and vertebrates.Ongoing GC-biased evolution is widespread in the human genome and enriched near recombination hot spots.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Extreme recombination frequencies shape genome variation and evolution in the honeybee, Apis melliferaGC-Content evolution in bacterial genomes: the biased gene conversion hypothesis expands.Quantification of GC-biased gene conversion in the human genome.GC-biased gene conversion in yeast is specifically associated with crossovers: molecular mechanisms and evolutionary significanceLong runs of homozygosity are enriched for deleterious variation.The influence of genomic context on mutation patterns in the human genome inferred from rare variants.Analytical Biases Associated with GC-Content in Molecular Evolution.GC-biased gene conversion links the recombination landscape and demography to genomic base composition: GC-biased gene conversion drives genomic base composition across a wide range of species.Phylogenomics Controlling for Base Compositional Bias Reveals a Single Origin of Eusociality in Corbiculate Bees.Codon usage and codon pair patterns in non-grass monocot genomes.Determinants of the Efficacy of Natural Selection on Coding and Noncoding Variability in Two Passerine Species.1000 human genomes carry widespread signatures of GC biased gene conversion.
P2860
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P2860
Meiotic recombination favors the spreading of deleterious mutations in human populations.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@ast
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@en
type
label
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@ast
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@en
prefLabel
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@ast
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@en
P2093
P2860
P50
P356
P1433
P1476
Meiotic recombination favors the spreading of deleterious mutations in human populations.
@en
P2093
Anamaria Necşulea
Christian Gautier
Dominique Mouchiroud
Peter D Stenson
P2860
P304
P356
10.1002/HUMU.21407
P577
2011-01-25T00:00:00Z