Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. - Wikidata - thesis-toulmin - TriplyDB

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.

http://www.wikidata.org/entity/Q30415907

about

Heterogeneity in the lymphatic vascular system and its origin New Strategies for the Treatment of Solid Tumors with CAR-T Cells T Lymphocyte-Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer Modes of Antigen Presentation by Lymph Node Stromal Cells and Their Immunological Implications Emerging roles of lymphatic endothelium in regulating adaptive immunity.High Endothelial Venules and Lymphatic Vessels in Tertiary Lymphoid Organs: Characteristics, Functions, and Regulation Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Revisiting the Mechanisms of CNS Immune Privilege.Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction Regulation of T-cell Tolerance by Lymphatic Endothelial Cells.Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment.Lymphatic endothelial cells - key players in regulation of tolerance and immunity Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance.Endothelial cell dysfunction in viral hemorrhage and edema.Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy Interplay between Inflammatory Responses and Lymphatic Vessels.Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes.Lymphangiogenesis is induced by mycobacterial granulomas via vascular endothelial growth factor receptor-3 and supports systemic T-cell responses against mycobacterial antigen.Lymphatic system: an active pathway for immune protection The lymph node microenvironment and its role in the progression of metastatic cancer.Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth Nivolumab in Resected and Unresectable Metastatic Melanoma: Characteristics of Immune-Related Adverse Events and Association with Outcomes.The Lymphatic System in Disease Processes and Cancer Progression Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation.The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment.Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells.Shaping of Peripheral T Cell Responses by Lymphatic Endothelial Cells.Mechanisms of lymphatic metastasis.Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation Bidirectional Crosstalk between Lymphatic Endothelial Cell and T Cell and Its Implications in Tumor Immunity.Emerging Roles of Lymphatic Vasculature in Immunity.Efficient Presentation of Multiple Endogenous Epitopes to Both CD4+ and CD8+ Diabetogenic T Cells for Tolerance Betting on improved cancer immunotherapy by doubling down on CD134 and CD137 co-stimulation.The inflammatory response of lymphatic endothelium.Lymphatic vessels: new targets for the treatment of inflammatory diseases.Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.

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P2860

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.

http://www.wikidata.org/entity/Q30415907

description

2012 nî lūn-bûn

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2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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Lymphatic endothelial cells in ...... D-1 expression on CD8 T cells.

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BLOOD-2012-04-427013

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Lymphatic endothelial cells in ...... D-1 expression on CD8 T cells.

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Adam J Adler

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Anthony T Vella

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Cynthia J Guidi

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Eric F Tewalt

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Hui Qiao

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Jarish N Cohen

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Kenneth S Tung

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Lieping Chen

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Mark R Conaway

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Sherin J Rouhani

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P2860

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand

Deletional tolerance mediated by extrathymic Aire-expressing cells

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Restoring function in exhausted CD8 T cells during chronic viral infection

The role of the PD-1 pathway in autoimmunity and peripheral tolerance

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

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230885180

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