Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes
about
Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetesIslet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.High glucose aggravates the detrimental effects of pancreatic stellate cells on Beta-cell functionMaintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response.Eukaryotic initiation factor 5A plays an essential role in luteinizing hormone receptor regulationDeoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.Whole blood gene expression profiles in insulin resistant Latinos with the metabolic syndrome.Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.Global quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells.Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cellsDetection of islet β-cell death in vivo by multiplex PCR analysis of differentially methylated DNA.Characterization of a novel polyclonal anti-hypusine antibody.Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic MiceLinker-Region Modified Derivatives of the Deoxyhypusine Synthase Inhibitor CNI-1493 Suppress HIV-1 Replication.Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome.Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes.Polyamine Metabolism and Oxidative Protein Folding in the ER as ROS-Producing Systems Neglected in Virology.
P2860
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P2860
Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@ast
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@en
type
label
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@ast
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@en
prefLabel
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@ast
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@en
P2093
P2860
P356
P1476
Inhibition of deoxyhypusine sy ...... lum stress and type 2 diabetes
@en
P2093
Bernhard Maier
Dhananjay Gupta
James Ficorilli
Krister Bokvist
Reiesha D Robbins
Takeshi Ogihara
Thomas B Farb
P2860
P304
39943-39952
P356
10.1074/JBC.M110.170142
P407
P577
2010-10-18T00:00:00Z