Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts - Wikidata - thesis-toulmin - TriplyDB

Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts

Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts

http://www.wikidata.org/entity/Q30437196

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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.Computational analysis of the spatiotemporal coordination of polarized PI3K and Rac1 activities in micro-patterned live cells Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg Random versus directionally persistent cell migration Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism Prediction of sphingosine 1-phosphate-stimulated endothelial cell migration rates using biochemical measurements Nerve growth factor induces axonal filopodia through localized microdomains of phosphoinositide 3-kinase activity that drive the formation of cytoskeletal precursors to filopodia.The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration.The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling.Directional persistence of cell migration coincides with stability of asymmetric intracellular signaling.A comparison of mathematical models for polarization of single eukaryotic cells in response to guided cues.Directed migration of cancer cells guided by the graded texture of the underlying matrix.Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motility.Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin In chemotaxing fibroblasts, both high-fidelity and weakly biased cell movements track the localization of PI3K signaling.Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein.Quantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer.Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF.Fibroblasts Lead the Way: A Unified View of 3D Cell Motility A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns NG2/CSPG4-collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion.ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips Time series modeling of live-cell shape dynamics for image-based phenotypic profiling.Intracellular encoding of spatiotemporal guidance cues in a self-organizing signaling system for chemotaxis in Dictyostelium cells Migration of connective tissue-derived cells is mediated by ultra-low concentration gradient fields of EGF.Excitable signal transduction induces both spontaneous and directional cell asymmetries in the phosphatidylinositol lipid signaling system for eukaryotic chemotaxis Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes.Quantitative analysis of phosphoinositide 3-kinase (PI3K) signaling using live-cell total internal reflection fluorescence (TIRF) microscopy.Mechanochemical feedback underlies coexistence of qualitatively distinct cell polarity patterns within diverse cell populations.Live imaging reveals distinct modes of neutrophil and macrophage migration within interstitial tissues.Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

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Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts

http://www.wikidata.org/entity/Q30437196

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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name

Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

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Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

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type

label

Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

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Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

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prefLabel

Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

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Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

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P1433

Journal of Cell Science

P1476

Spontaneous phosphoinositide 3 ...... andom migration of fibroblasts

@en

P2093

Adam T Melvin

http://www.w3.org/2001/XMLSchema#string

Chun-Chao Wang

http://www.w3.org/2001/XMLSchema#string

Jason M Haugh

http://www.w3.org/2001/XMLSchema#string

John J Rhoden

http://www.w3.org/2001/XMLSchema#string

Matej Krajcovic

http://www.w3.org/2001/XMLSchema#string

Michael C Weiger

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2

Cell migration: integrating signals from front to back

Cellular motility driven by assembly and disassembly of actin filaments

Cell migration: a physically integrated molecular process

Rho GTPases in cell biology

FAK integrates growth-factor and integrin signals to promote cell migration

Synthesis and function of 3-phosphorylated inositol lipids

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

P304

313-323

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scholarly article

P356

10.1242/JCS.037564

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P407

P433

Pt 3

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P478

122

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P577

2009-01-06T00:00:00Z

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19126672

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2724728

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