Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.
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Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosisImaging Axonal Degeneration and Repair in Preclinical Animal Models of Multiple SclerosisIntegrins Influence the Size and Dynamics of Signaling Microclusters in a Pyk2-dependent MannerHigh avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral functionA major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.Defects in the acquisition of tumor-killing capability of CD8+ cytotoxic T cells in streptozotocin-induced diabetic miceThe regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapseIn vivo polarization of IFN-gamma at Kupfer and non-Kupfer immunological synapses during the clearance of virally infected brain cells.Cytotoxic immunological synapses do not restrict the action of interferon-γ to antigenic target cells.Evaluating frequency and quality of pathogen-specific T cells.Mycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cellsSynergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligaseThe effect of gentamicin-induced readthrough on a novel premature termination codon of CD18 leukocyte adhesion deficiency patients.New insights into the role of EMT in tumor immune escape.Cytotoxic immunological synapses.A signaling network stimulated by β2 integrin promotes the polarization of lytic granules in cytotoxic cellsImmune-mediated changes in actinic keratosis following topical treatment with imiquimod 5% cream.NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha.Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells.Activation, coactivation, and costimulation of resting human natural killer cellsTh1 and Th2 cells form morphologically distinct immunological synapses.Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.Transient Surface CCR5 Expression by Naive CD8+ T Cells within Inflamed Lymph Nodes Is Dependent on High Endothelial Venule Interaction and Augments Th Cell-Dependent Memory ResponseAntigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane.Endogenous tumor-reactive CD8(+) T cells are differentiated effector cells expressing high levels of CD11a and PD-1 but are unable to control tumor growth.T-cell activation through immunological synapses and kinapses.Two-photon imaging of effector T-cell behavior: lessons from a tumor model.Vav1-phospholipase C-γ1 (Vav1-PLC-γ1) pathway initiated by T cell antigen receptor (TCRγδ) activation is required to overcome inhibition by ubiquitin ligase Cbl-b during γδT cell cytotoxicity.Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane.Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cellsSignal transduction during activation and inhibition of natural killer cells.Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.Controlling natural killer cell responses: integration of signals for activation and inhibition.Functional anatomy of T cell activation and synapse formation.Understanding the structure and function of the immunological synapseDiversity in immunological synapse structure.New insights into the T cell synapse from single molecule techniques.Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.
P2860
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P2860
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@ast
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@en
type
label
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@ast
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@en
prefLabel
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@ast
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@en
P2093
P2860
P356
P1476
Distinct role of lymphocyte fu ...... ty by cytotoxic T lymphocytes.
@en
P2093
Kristina Somersalo
Nadia Anikeeva
Tasha N Sims
V Kaye Thomas
Yuri Sykulev
P2860
P304
P356
10.1073/PNAS.0502467102
P407
P577
2005-04-25T00:00:00Z