Allosteric modulation of metabotropic glutamate receptors.
about
The search for novel analgesics: targets and mechanismsNeurobiological Insights from mGlu Receptor Allosteric Modulation.Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X.Sniffer patch laser uncaging response (SPLURgE): an assay of regional differences in allosteric receptor modulation and neurotransmitter clearanceTherapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5).Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.Kainate receptor signaling in pain pathways.Allosteric modulation and functional selectivity of G protein-coupled receptors.The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu4 receptors in rodentsSilent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.Drug Design Strategies for GPCR Allosteric Modulators.Dissecting the Signaling Pathways Involved in the Crosstalk between Metabotropic Glutamate 5 and Cannabinoid Type 1 Receptors.Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration.Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.Is there room for non-dopaminergic treatment in Parkinson disease?[G protein-coupled receptors in the spot light].Adenosine A₂A receptors permit mGluR5-evoked tyrosine phosphorylation of NR2B (Tyr1472) in rat hippocampus: a possible key mechanism in NMDA receptor modulation.Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation
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P2860
Allosteric modulation of metabotropic glutamate receptors.
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Allosteric modulation of metabotropic glutamate receptors.
@ast
Allosteric modulation of metabotropic glutamate receptors.
@en
type
label
Allosteric modulation of metabotropic glutamate receptors.
@ast
Allosteric modulation of metabotropic glutamate receptors.
@en
prefLabel
Allosteric modulation of metabotropic glutamate receptors.
@ast
Allosteric modulation of metabotropic glutamate receptors.
@en
P2860
P1476
Allosteric modulation of metabotropic glutamate receptors.
@en
P2093
Douglas J Sheffler
Jerri M Rook
P2860
P356
10.1016/B978-0-12-385952-5.00010-5
P577
2011-01-01T00:00:00Z