Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice. - Wikidata - thesis-toulmin - TriplyDB

Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.

Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.

http://www.wikidata.org/entity/Q30494594

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Adult Astrogenesis and the Etiology of Cortical Neurodegeneration Neuroinflammation in Parkinson's disease and its potential as therapeutic target Elusive roles for reactive astrocytes in neurodegenerative diseases Glia and alpha-synuclein in neurodegeneration: A complex interaction Astrocytes conspire with neurons during progression of neurological disease The role of free radicals in the aging brain and Parkinson's Disease: convergence and parallelism Genetically engineered mouse models of Parkinson's disease The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?Glia: an emerging target for neurological disease therapy Spreading of pathology in neurodegenerative diseases: a focus on human studies The ubiquitin proteasome system in glia and its role in neurodegenerative diseases Transplanted Neural Stem Cells: Playing a Neuroprotective Role by Ceruloplasmin in the Substantia Nigra of PD Model Rats?Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity.Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice A Refined Bead-Free Method to Identify Astrocytic Exosomes in Primary Glial Cultures and Blood Plasma Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice.Targeting cyclooxygenases-1 and -2 in neuroinflammation: Therapeutic implications.Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease.Expression of mutant alpha-synuclein modulates microglial phenotype in vitro Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain Electroacupuncture remediates glial dysfunction and ameliorates neurodegeneration in the astrocytic α-synuclein mutant mouse model Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies.Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1 Direct detection of alpha synuclein oligomers in vivo Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.The Synucleinopathies: Twenty Years On.Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts.Tracking extranigral degeneration in animal models of Parkinson's disease: quest for effective therapeutic strategies.Targeting cyclooxygenase-2 in depression is not a viable therapeutic approach and may even aggravate the pathophysiology underpinning depression.Defective autophagy in Parkinson's disease: role of oxidative stress.The role of glia in α-synucleinopathies.Dysfunction of two lysosome degradation pathways of α-synuclein in Parkinson's disease: potential therapeutic targets?Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration Review: microglia in protein aggregation disorders: friend or foe?The role of inflammation in sporadic and familial Parkinson's disease.Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease.

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Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.

http://www.wikidata.org/entity/Q30494594

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Astrocytic expression of Parki ...... ses neurodegeneration in mice.

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Astrocytic expression of Parki ...... ses neurodegeneration in mice.

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Astrocytic expression of Parki ...... ses neurodegeneration in mice.

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Astrocytic expression of Parki ...... ses neurodegeneration in mice.

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Astrocytic expression of Parki ...... ses neurodegeneration in mice.

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Astrocytic expression of Parki ...... uses neurodegeneration in mice

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Cai-Xia Long

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Chengsong Xie

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Lixin Sun

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Xian Lin

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P2860

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

The astrocyte odyssey

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

alpha-Synuclein locus triplication causes Parkinson's disease

Alpha-synuclein in Lewy bodies

Astrocyte-endothelial interactions at the blood-brain barrier

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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Parkinson's disease

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2873589

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