TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
about
Transient receptor potential (TRP) channels as drug targets for diseases of the digestive systemSpecies-specific temperature sensitivity of TRPA1TRP ion channels in thermosensation, thermoregulation and metabolismTRPA1 as a drug target--promise and challengesThe functional and anatomical dissection of somatosensory subpopulations using mouse geneticsCold hypersensitivity increases with age in mice with sickle cell diseaseUpregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective rolesPharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in miceTRPA1 contributes to cold hypersensitivityMolecular mechanisms of temperature adaptationRole of TRPA1 in Acute Cardiopulmonary Toxicity of Inhaled AcroleinIon channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation.Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the ratCutaneous TRPM8-expressing sensory afferents are a small population of neurons with unique firing properties.Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain.An approach to identify microRNAs involved in neuropathic pain following a peripheral nerve injury.Labeled lines meet and talk: population coding of somatic sensations.Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling.A novel behavioral assay for measuring cold sensation in mice.A dynamic set point for thermal adaptation requires phospholipase C-mediated regulation of TRPM8 in vivoPlant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channelsSensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons.Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol.Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera.Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception.TRPV1-lineage neurons are required for thermal sensation.Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8.Scraping through the ice: uncovering the role of TRPM8 in cold transductionThe effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment deviceCentral connectivity of transient receptor potential melastatin 8-expressing axons in the brain stem and spinal dorsal hornAMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodyniaHow does morphology relate to function in sensory arbors?Perineural pretreatment of bee venom attenuated the development of allodynia in the spinal nerve ligation injured neuropathic pain model; an experimental studyA simple and inexpensive method for determining cold sensitivity and adaptation in mice.Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.Regulation of TRPM8 channel activityThe molecular and cellular basis of thermosensation in mammals.Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensationThe preventive effect of resiniferatoxin on the development of cold hypersensitivity induced by spinal nerve ligation: involvement of TRPM8Thermosensitive transient receptor potential (TRP) channel agonists and their role in mechanical, thermal and nociceptive sensations as assessed using animal models.
P2860
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P2860
TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@ast
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@en
type
label
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@ast
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@en
prefLabel
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@ast
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@en
P2093
P2860
P1433
P1476
TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo
@en
P2093
Amber Bifolck-Fisher
David D McKemy
Diana M Bautista
Wendy M Knowlton
P2860
P304
P356
10.1016/J.PAIN.2010.05.021
P407
P577
2010-06-12T00:00:00Z