Inhibition of aldose reductase prevents colon cancer metastasis
about
An old NSAID revisited: crystal structure of aldose reductase in complex with sulindac at 1.0 Å supports a novel mechanism for its anticancer and antiproliferative effectsIdentification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug designStructural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10Progress toward in vivo use of siRNAs-IIAldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice.Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat.Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.4-Hydroxynonenal in the pathogenesis and progression of human diseases.Critical analysis of carcinogenicity study outcomes. Relationship with pharmacological properties.SDF-1/CXCR4 axis promotes directional migration of colorectal cancer cells through upregulation of integrin αvβ6.Preventive cancer stem cell-based vaccination reduces liver metastasis development in a rat colon carcinoma syngeneic model.Expression of the Aldo-Ketoreductases AKR1B1 and AKR1B10 in Human CancersAldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expressionAldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity.Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells.The use of dimethylsulfoxide as a solvent in enzyme inhibition studies: the case of aldose reductase.Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction.Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice.
P2860
Q27675028-CE9F4DAC-CE81-4F15-92C7-D3196341A51AQ27689445-071BAD37-6597-45E6-9866-515501F9B153Q27702584-D4E60294-A608-44E7-B163-B62A2A45A627Q28255877-0B76F1E8-65A8-4140-B03D-2A451B65A88CQ34608582-49487E42-6C72-4F4A-8E37-D558F1F7953DQ35723290-D0383737-4E7E-463F-9F47-1A8EBEFD9B4CQ36006910-58E33F8E-2188-4844-894B-0488E1D5F47BQ36585331-C65FC2AE-07DD-45B4-8FCE-6643A970AF31Q38121162-A00FA7DF-C8CD-41D7-9B13-F4B780A19391Q38818082-AC33ECE2-9CC9-46AC-90A0-AD096656A8E2Q39088984-4737202D-9541-4699-A307-5A3C4D2D5841Q39236143-F32CE861-3299-4406-8D70-842E32D626EDQ41815150-933FD5A9-A39B-401F-A7DE-487A38B63AADQ41854605-B451B4DE-59E5-40E5-A75D-75CEEC72BEFFQ41878176-B9E0E1A4-B35D-416A-B87A-D60C3178B30AQ41943341-70B709A0-D3D3-494B-8CCF-1C865878978AQ47685602-0D3F0960-815C-4C25-B4EA-110EF471B258Q47879109-13B9C543-84B0-4651-9892-FC500C3C36B6Q49848276-9892CB31-FB66-42ED-9D5F-8DE83192D757Q52755069-27A5A078-C826-4F0F-9AB7-287EA41A80B0Q53183762-6B62F869-E1FB-4DEF-B878-80B154693431
P2860
Inhibition of aldose reductase prevents colon cancer metastasis
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Inhibition of aldose reductase prevents colon cancer metastasis
@ast
Inhibition of aldose reductase prevents colon cancer metastasis
@en
type
label
Inhibition of aldose reductase prevents colon cancer metastasis
@ast
Inhibition of aldose reductase prevents colon cancer metastasis
@en
prefLabel
Inhibition of aldose reductase prevents colon cancer metastasis
@ast
Inhibition of aldose reductase prevents colon cancer metastasis
@en
P2093
P2860
P356
P1433
P1476
Inhibition of aldose reductase prevents colon cancer metastasis
@en
P2093
Aramati B M Reddy
Ashish Saxena
B Mark Evers
Ravinder Tammali
Sanjay Awasthi
Satish K Srivastava
Suimin Qiu
P2860
P304
P356
10.1093/CARCIN/BGR102
P407
P577
2011-06-03T00:00:00Z