Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
about
Molecular dynamics simulations of membrane proteins and their interactions: from nanoscale to mesoscaleFormation of raft-like assemblies within clusters of influenza hemagglutinin observed by MD simulationsCellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated ProteinsTrace membrane additives affect lipid phases with distinct mechanisms: a modified Ising model.Imaging the lipid-phase-dependent pore formation of equinatoxin II in droplet interface bilayers.Molecular dynamics exploration of poration and leaking caused by Kalata B1 in HIV-infected cell membrane compared to host and HIV membranesDomain Stability in Biomimetic Membranes Driven by Lipid PolyunsaturationModulation of a small two-domain lipid vesicle by linactants.Dynamic multiprotein assemblies shape the spatial structure of cell signalingMechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.Membrane-mediated regulation of the intrinsically disordered CD3ϵ cytoplasmic tail of the TCR.Overview of simulation studies on the enzymatic activity and conformational dynamics of the GTPase Ras.Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions.GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.Formation and domain partitioning of H-ras peptide nanoclusters: effects of peptide concentration and lipid composition.Reversible Effects of Peptide Concentration and Lipid Composition on H-Ras Lipid Anchor ClusteringMapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution.Oncogenic K-Ras Binds to an Anionic Membrane in Two Distinct Orientations: A Molecular Dynamics Analysis.Plasma membrane regulates Ras signaling networks.Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains.The Role of Signaling via Aqueous Pore Formation in Resistance Responses to Amphotericin BLessons from computer simulations of Ras proteins in solution and in membraneMolecular pathways: sterols and receptor signaling in cancer.Deformation of a Two-domain Lipid Bilayer due to Asymmetric Insertion of Lipid-modified Ras Peptides.The spatial structure of cell signaling systems.Defining the membrane disruption mechanism of kalata B1 via coarse-grained molecular dynamics simulations.The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering.Cholesterol modulates the dimer interface of the β₂-adrenergic receptor via cholesterol occupancy sites.Membrane Remodeling by Surface-Bound Protein Aggregates: Insights from Coarse-Grained Molecular Dynamics Simulation.Perspective on the Martini model.Adenylate cyclase-centred microdomains.Review structure- and dynamics-based computational design of anticancer drugs.Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation.Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment.CHARMM-GUI PACE CG Builder for solution, micelle, and bilayer coarse-grained simulationsDrugging Ras GTPase: a comprehensive mechanistic and signaling structural view.Emerging role of chemoprotective agents in the dynamic shaping of plasma membrane organization.Intrinsic protein disorder in oncogenic KRAS signaling.Cooperative Clustering Digitizes Biochemical Signaling and Enhances its Fidelity.The cellular membrane as a mediator for small molecule interaction with membrane proteins.
P2860
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P2860
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@ast
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@en
type
label
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@ast
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@en
prefLabel
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@ast
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@en
P2093
P2860
P356
P1476
Organization, dynamics, and segregation of Ras nanoclusters in membrane domains.
@en
P2093
Alemayehu A Gorfe
John F Hancock
Lorant Janosi
Zhenlong Li
P2860
P304
P356
10.1073/PNAS.1200773109
P407
P577
2012-05-04T00:00:00Z