Characterization and regulation of an additional actin-filament-binding site in large isoforms of the stereocilia actin-bundling protein espin
about
Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear.Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins.Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of EspinComputational Modelling of NF-κB Activation by IL-1RI and Its Co-Receptor TILRR, Predicts a Role for Cytoskeletal Sequestration of IκBα in Inflammatory SignallingMyosin III-mediated cross-linking and stimulation of actin bundling activity of Espin.Stereocilia morphogenesis and maintenance through regulation of actin stability.The stable actin core of mechanosensory stereocilia features continuous turnover of actin cross-linkers
P2860
Q27308986-BB40E1D8-ED9B-495F-8A4F-3ADC72EA7E33Q27329412-DD5E166A-00C1-4E56-BF5E-BEE03B01ABC2Q29347270-DFD69A93-FC69-4C70-8203-CAAE9EE075E7Q30644335-C33B616C-6035-46BF-AFA1-1B6168EA3751Q30659759-C3973E4D-7232-4A81-A790-186F70602EB7Q30854396-5627F5B6-DB18-494B-BC72-B9C877193A15Q35673886-F55AE1C5-6DC9-416E-86C8-5AE7717CB485Q36594218-FCCC6685-29E1-42BE-B0B9-4F1A0BE9DEFCQ38938244-03FD5793-E67E-40DE-9DA6-70EAB501D9D4Q58806158-3337052B-D9C0-4D2E-9082-A3B39DD2A8E0
P2860
Characterization and regulation of an additional actin-filament-binding site in large isoforms of the stereocilia actin-bundling protein espin
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Characterization and regulatio ...... a actin-bundling protein espin
@ast
Characterization and regulatio ...... a actin-bundling protein espin
@en
type
label
Characterization and regulatio ...... a actin-bundling protein espin
@ast
Characterization and regulatio ...... a actin-bundling protein espin
@en
prefLabel
Characterization and regulatio ...... a actin-bundling protein espin
@ast
Characterization and regulatio ...... a actin-bundling protein espin
@en
P2860
P356
P1476
Characterization and regulatio ...... a actin-bundling protein espin
@en
P2093
Dina M Beeler
Lili Zheng
P2860
P304
P356
10.1242/JCS.143255
P407
P577
2014-01-14T00:00:00Z