Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells - Wikidata - thesis-toulmin - TriplyDB

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

http://www.wikidata.org/entity/Q30845849

about

Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis Modeling complex genetic and environmental influences on comorbid bipolar disorder with tobacco use disorder.Endoplasmic Reticulum Stress-Associated Chaperones, Bip/GRP78 and Calnexin are Overexpressed in Keratocystic Odontogenic Tumours Z α1-antitrypsin confers a proinflammatory phenotype that contributes to chronic obstructive pulmonary disease A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue.Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator PKR-dependent CHOP induction limits hyperoxia-induced lung injury.CCN1 secretion induced by cigarette smoking extracts augments IL-8 release from bronchial epithelial cells.Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta.Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis.Smoking and adipose tissue inflammation suppress leptin expression in Japanese obese males: potential mechanism of resistance to weight loss among Japanese obese smokers Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study.Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase Cigarette smoke and CFTR: implications in the pathogenesis of COPD Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure.Autophagy in the lung The unfolded protein response in lung disease.Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease.The biological and therapeutic relevance of mRNA translation in cancer.COX inhibitors for airway inflammation.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins.The UPR and lung disease.DAMPs activating innate and adaptive immune responses in COPD.The integrated stress response in lung disease.Proteomics for systems toxicology.Cross-talk between apoptosis and autophagy in lung epithelial cell death.Non-coding RNAs in the pathogenesis of COPD.Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells.Effects of RNAi-mediated TUSC3 silencing on radiation-induced autophagy and radiation sensitivity of human lung adenocarcinoma cell line A549 under hypoxic condition.Role of Inflammation and Oxidative Stress in the Pathology of Ageing in COPD: Potential Therapeutic Interventions.Cigarette smoke increases Staphylococcus aureus biofilm formation via oxidative stress.Cigarette smoke induces endoplasmic reticulum stress response and proteasomal dysfunction in human alveolar epithelial cells.

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P2860

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

http://www.wikidata.org/entity/Q30845849

description

2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Cigarette smoke induces endopl ...... and malignant human lung cells

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Cigarette smoke induces endopl ...... and malignant human lung cells

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Cigarette smoke induces endopl ...... and malignant human lung cells

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Cigarette smoke induces endopl ...... and malignant human lung cells

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Cigarette smoke induces endopl ...... and malignant human lung cells

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Cigarette smoke induces endopl ...... and malignant human lung cells

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Andy Stinson

http://www.w3.org/2001/XMLSchema#string

Anthony P Albino

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Diana Gietl

http://www.w3.org/2001/XMLSchema#string

Ellen Jorgensen

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Jin Yang

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Lin Shan

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P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

Epidemiology of Lung Cancer

Cigarette smoking and cancer risk: modeling total exposure and intensity

Inflammation and lung cancer: roles of reactive oxygen/nitrogen species

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

Signal integration in the endoplasmic reticulum unfolded protein response

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8

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1007935512

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18694499

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endoplasmic reticulum

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2527015

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