Phage-displayed peptides bind to the malarial protein apical membrane antigen-1 and inhibit the merozoite invasion of host erythrocytes.
about
Host-parasite interaction: multiple sites in the Plasmodium vivax tryptophan-rich antigen PvTRAg38 interact with the erythrocyte receptor band 3Identification of a highly antigenic linear B cell epitope within Plasmodium vivax apical membrane antigen 1 (AMA-1)Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptideA structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteinsBinding hot spot for invasion inhibitory molecules on Plasmodium falciparum apical membrane antigen 1Peptide mimotopes selected from a random peptide library for diagnosis of Epstein-Barr virus infectionRNA mutagenesis yields highly diverse mRNA libraries for in vitro protein evolution.Receptor-based identification of an inhibitory peptide against blood stage malaria.Identification of peptide ligands for targeting to the blood-brain barrierPeptide inhibitors of the malaria surface protein, apical membrane antigen 1: identification of key binding residuesInteraction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites.Conditional expression of Toxoplasma gondii apical membrane antigen-1 (TgAMA1) demonstrates that TgAMA1 plays a critical role in host cell invasionSelection of binding targets in parasites using phage-display and aptamer libraries in vivo and in vitro.The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody.Erythrocyte invasion by Babesia bovis merozoites is inhibited by polyclonal antisera directed against peptides derived from a homologue of Plasmodium falciparum apical membrane antigen 1.Apical membrane antigen 1, a major malaria vaccine candidate, mediates the close attachment of invasive merozoites to host red blood cells.Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.Heterologous expression of Plasmodium vivax apical membrane antigen 1 (PvAMA1) for binding peptide selection.Bioinformatic Identification of Peptidomimetic-Based Inhibitors against Plasmodium falciparum Antigen AMA1.Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning.A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage.Administration of naloxone in combination with recombinant Plasmodium vivax AMA-1 in BALB/c mice induces mixed Th1/Th2 immune responses.Antimalarial drug discovery targeting apical membrane antigen 1
P2860
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P2860
Phage-displayed peptides bind to the malarial protein apical membrane antigen-1 and inhibit the merozoite invasion of host erythrocytes.
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Phage-displayed peptides bind ...... invasion of host erythrocytes.
@ast
Phage-displayed peptides bind ...... invasion of host erythrocytes.
@en
type
label
Phage-displayed peptides bind ...... invasion of host erythrocytes.
@ast
Phage-displayed peptides bind ...... invasion of host erythrocytes.
@en
prefLabel
Phage-displayed peptides bind ...... invasion of host erythrocytes.
@ast
Phage-displayed peptides bind ...... invasion of host erythrocytes.
@en
P2093
P2860
P356
P1476
Phage-displayed peptides bind ...... invasion of host erythrocytes
@en
P2093
Alan Thomas
Andrew M Coley
Anton Dluzewski
Felomena Li
Michael Foley
P2860
P304
50303-50310
P356
10.1074/JBC.M207985200
P407
P577
2002-10-14T00:00:00Z