Cholinergic neuronal defect without cell loss in Huntington's disease. - Wikidata - thesis-toulmin - TriplyDB

Cholinergic neuronal defect without cell loss in Huntington's disease.

Cholinergic neuronal defect without cell loss in Huntington's disease.

http://www.wikidata.org/entity/Q33258207

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Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease Striatal cholinergic interneuron regulation and circuit effects Genetics and neuropathology of Huntington's disease Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission.A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Transcriptional activation of REST by Sp1 in Huntington's disease models Differential Alteration in Expression of Striatal GABAAR Subunits in Mouse Models of Huntington's Disease Development of allosteric modulators of GPCRs for treatment of CNS disorders Abnormal motor cortex excitability in preclinical and very early Huntington's disease.Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1α Reduced expression of the vesicular acetylcholine transporter and neurotransmitter content affects synaptic vesicle distribution and shape in mouse neuromuscular junction.Specific reactions of different striatal neuron types in morphology induced by quinolinic acid in rats.Enhanced GABAergic Inputs Contribute to Functional Alterations of Cholinergic Interneurons in the R6/2 Mouse Model of Huntington's Disease Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice.Radiation dosimetry of [(18)F]VAT in nonhuman primates.Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.Cholinergic Interneurons Amplify Corticostriatal Synaptic Responses in the Q175 Model of Huntington's Disease.Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase.Pharmacologic approaches to the treatment of Huntington's disease.Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?Reassessment of the role of the central cholinergic system.NRSF: an angel or a devil in neurogenesis and neurological diseases.Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease.Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI).MicroRNA-432 contributes to dopamine cocktail and retinoic acid induced differentiation of human neuroblastoma cells by targeting NESTIN and RCOR1 genes.Targeting the Cholinergic System to Develop a Novel Therapy for Huntington's Disease Dysregulation of Corticostriatal Connectivity in Huntington's Disease: A Role for Dopamine Modulation Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy.1-Methyl-4-propan-2-ylbenzene from Thymus vulgaris Attenuates Cholinergic Dysfunction.Cholinergic interneurons in the Q140 knockin mouse model of Huntington's disease: Reductions in dendritic branching and thalamostriatal input.Extrinsic Sources of Cholinergic Innervation of the Striatal Complex: A Whole-Brain Mapping Analysis.Centrality of striatal cholinergic transmission in Basal Ganglia function.Progressive polyuria without vasopressin neuron loss in a mouse model for familial neurohypophysial diabetes insipidus.Electrochemical processes and mechanistic aspects of field-effect sensors for biomolecules.Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.Effect of walnut protein hydrolysate on scopolamine-induced learning and memory deficits in mice.Age-dependent dystonia in striatal Gγ7 deficient mice is reversed by the dopamine D2 receptor agonist pramipexole.Disrupted striatal neuron inputs and outputs in Huntington's disease.

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P2860

Cholinergic neuronal defect without cell loss in Huntington's disease.

http://www.wikidata.org/entity/Q33258207

description

2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Cholinergic neuronal defect without cell loss in Huntington's disease.

@ast

Cholinergic neuronal defect without cell loss in Huntington's disease.

@en

type

label

Cholinergic neuronal defect without cell loss in Huntington's disease.

@ast

Cholinergic neuronal defect without cell loss in Huntington's disease.

@en

prefLabel

Cholinergic neuronal defect without cell loss in Huntington's disease.

@ast

Cholinergic neuronal defect without cell loss in Huntington's disease.

@en

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P1433

Human Molecular Genetics

P1476

Cholinergic neuronal defect without cell loss in Huntington's disease.

@en

P2093

Elisabet Englund

http://www.w3.org/2001/XMLSchema#string

Hinfan Chung

http://www.w3.org/2001/XMLSchema#string

Marion L C Maat-Schieman

http://www.w3.org/2001/XMLSchema#string

Richard L M Faull

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Ruben Smith

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Sara Rundquist

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Yong-Jian Liu

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P2860

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

A new and rapid colorimetric determination of acetylcholinesterase activity

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

Regulation of the cholinergic gene locus by the repressor element-1 silencing transcription factor/neuron restrictive silencer factor (REST/NRSF)

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

Developments of a water-maze procedure for studying spatial learning in the rat

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease.

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3119-3131

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scholarly article

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10.1093/HMG/DDL252

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21

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15

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Raymund A. C. Roos

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2006-09-20T00:00:00Z

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6806297

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16987871

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P921

Huntington disease