Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery.
about
Encoded combinatorial chemistrySemisynthetic combinatorial antibody libraries: a chemical solution to the diversity problemAn algorithm for protein engineering: simulations of recursive ensemble mutagenesisGeneration and screening of an oligonucleotide-encoded synthetic peptide libraryHigh-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding siteDiscovery of active proteins directly from combinatorial randomized protein libraries without display, purification or sequencing: identification of novel zinc finger proteinsBacteriophages and their applications in the diagnosis and treatment of hepatitis B virus infectionCombinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope GlycoproteinBiochemical and structural characterization of SplD protease from Staphylococcus aureusSubstrate specificity and inhibition studies of human serotonin N-acetyltransferaseCombinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusionIdentification and characterization of novel antimicrobial decapeptides generated by combinatorial chemistryIdentification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical libraryAn inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replicationMachine learning assisted design of highly active peptides for drug discoveryWhat is a "DNA-Compatible" Reaction?Synthesis and application of peptide dendrimers as protein mimetics.Techniques for molecular imaging probe designA combinatorial peptoid library for the identification of novel MSH and GRP/bombesin receptor ligands.Semi-automated high throughput combinatorial solid-phase organic synthesis.Towards vast libraries of scaffold-diverse, conformationally constrained oligomers.Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides.Library design concepts and implementation strategies.Screening of ligand binding on melatonin receptor using non-peptide combinatorial libraries.Large-scale functional analysis using peptide or protein arrays.Advances in the use of synthetic combinatorial chemistry: mixture-based libraries.De novo sequencing of peptides on single resin beads by MALDI-FTICR tandem mass spectrometry.Successful identification of novel agents to control infectious diseases from screening mixture-based peptide combinatorial libraries in complex cell-based bioassays.Accurate MALDI-TOF/TOF sequencing of one-bead-one-compound peptide libraries with application to the identification of multiligand protein affinity agents using in situ click chemistry screeningGlobal analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors.An N-methyl-D-aspartate receptor channel blocker with neuroprotective activity.Peptide vaccines and peptide libraries.Sample size determination in combinatorial chemistryInteraction of RNA with phage display selected peptides analyzed by capillary electrophoresis mobility shift assay.Specificity and affinity motifs for Grb2 SH2-ligand interactionsDetermination of isokinetic ratios necessary for equimolar incorporation of carboxylic acids in the solid-phase synthesis of mixture-based combinatorial libraries.Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance.Identification of highest-affinity ligands by affinity selection from equimolar peptide mixtures generated by robotic synthesis.Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library.A new hybrid resin for stepwise screening of peptide libraries combined with single bead Edman sequencing.
P2860
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P2860
Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery.
description
1991 nî lūn-bûn
@nan
1991 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
name
Generation and use of syntheti ...... c research and drug discovery.
@ast
Generation and use of syntheti ...... c research and drug discovery.
@en
type
label
Generation and use of syntheti ...... c research and drug discovery.
@ast
Generation and use of syntheti ...... c research and drug discovery.
@en
prefLabel
Generation and use of syntheti ...... c research and drug discovery.
@ast
Generation and use of syntheti ...... c research and drug discovery.
@en
P2093
P356
P1433
P1476
Generation and use of syntheti ...... c research and drug discovery.
@en
P2093
P2888
P356
10.1038/354084A0
P407
P577
1991-11-01T00:00:00Z
P5875
P6179
1024306705