Human MutLalpha: the jack of all trades in MMR is also an endonuclease. - Wikidata - thesis-toulmin - TriplyDB

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

http://www.wikidata.org/entity/Q33343475

about

The C-Terminal Domain of the MutL Homolog from Neisseria gonorrhoeae Forms an Inverted Homodimer DNA mismatch repair in eukaryotes and bacteria Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity.Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.Proteasome inhibition rescues clinically significant unstable variants of the mismatch repair protein Msh2.Endonuclease activities of MutLα and its homologs in DNA mismatch repair.Structure and mechanism for DNA lesion recognition.Nucleases: diversity of structure, function and mechanism.Evidence for ATP-dependent structural rearrangement of nuclease catalytic site in DNA mismatch repair endonuclease MutL.Structural Features and Functional Dependency on β-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL Small-angle X-ray scattering analysis reveals the ATP-bound monomeric state of the ATPase domain from the homodimeric MutL endonuclease, a GHKL phosphotransferase superfamily protein.Bound nucleotide controls the endonuclease activity of mismatch repair enzyme MutL.

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Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

http://www.wikidata.org/entity/Q33343475

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

@ast

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

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type

label

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

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Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

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prefLabel

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

@ast

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

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J.DNAREP.2006.10.021

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P1476

Human MutLalpha: the jack of all trades in MMR is also an endonuclease.

@en

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Wei Yang

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P2860

Human exonuclease I is required for 5' and 3' mismatch repair

A defined human system that supports bidirectional mismatch-provoked excision

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

Insights into negative modulation of E. coli replication initiation from the structure of SeqA-hemimethylated DNA complex

Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis.

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135-139

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scholarly article

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10.1016/J.DNAREP.2006.10.021

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