PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.

PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.

Item
http://www.wikidata.org/entity/Q33377358
Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.Megakaryocytic programming by a transcriptional regulatory loop: A circle connecting RUNX1, GATA-1, and P-TEFb.A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.The transcription factor GATA1 regulates NBEAL2 expression through a long-distance enhancer.Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) impairs the regulation of apoptosis in megakaryocytes by activating NF-κB: a proteomic study.Therapeutic antibodies directed at G protein-coupled receptorsPhage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes.PACAP38/PAC1 signaling induces bone marrow-derived cells homing to ischemic brain.Characterization and use of a rabbit-anti-mouse VPAC1 antibody by flow cytometryDifferential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis.The contribution of platelet studies to the understanding of disease mechanisms in complex and monogenetic neurological disorders.Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor.Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome.Effect of VPAC1 Blockade on Adipose Tissue Formation and Composition in Mouse Models of Nutritionally Induced Obesity.Anagrelide platelet-lowering effect is due to inhibition of both megakaryocyte maturation and proplatelet formation: insight into potential mechanisms.
P2860

PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.

Item
http://www.wikidata.org/entity/Q33377358
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@ast
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@en
type
label
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@ast
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@en
prefLabel
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@ast
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
PACAP and its receptor VPAC1 regulate megakaryocyte maturation: therapeutic implications.
@en
P2093
P304
P31
P356
10.1182/BLOOD-2007-06-098558
P407
P433
P478
P50
P577
P5875
P698