Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome.
about
The contribution of mouse models to the understanding of constitutional thrombocytopeniaHematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsIn Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott-Aldrich Syndrome Protein-Deficient B Cells.Foamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndrome.Wiskott-Aldrich syndrome: a comprehensive review.Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.Autoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCIDWiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.Wiskott-Aldrich syndrome protein-deficient hematopoietic cells can be efficiently mobilized by granulocyte colony-stimulating factor.Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.Advances in basic and clinical immunology in 2011.Gene therapy for monogenic disorders of the bone marrow.Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans.B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome.Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.Efficacy of lentiviral mediated gene therapy in an Omenn syndrome Rag2 mouse model is not hindered by inflammation and immune dysregulation.Autonomous role of Wiskott-Aldrich Syndrome platelet deficiency in inducing autoimmunity and inflammation.Rare Genetic Blood Disease Modeling in Zebrafish
P2860
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P2860
Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@ast
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@en
type
label
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@ast
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@en
prefLabel
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@ast
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@en
P2093
P50
P1476
Lentiviral-mediated gene thera ...... l of Wiskott-Aldrich syndrome.
@en
P2093
Aisha Vanessa Sauer
Elena Draghici
Elena Fontana
Elisabetta Traggiai
Francesca Schena
Marco Catucci
Marita Bosticardo
Michela Locci
P304
1376-84.e5
P356
10.1016/J.JACI.2011.03.030
P407
P50
P577
2011-04-29T00:00:00Z