Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
about
Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapyRole of DNA polymerase κ in the maintenance of genomic stabilityEukaryotic DNA polymerase ζA broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesisStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4Structural insights into the assembly of human translesion polymerase complexesReplication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymeraseStructural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase ηThe mechanisms of UV mutagenesis.REV1 and polymerase ζ facilitate homologous recombination repairSimultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesionsDNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cellsThe transcription factor TFII-I promotes DNA translesion synthesis and genomic stabilityThe vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled siteReplication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts.Contributions of nucleotide excision repair, DNA polymerase eta, and homologous recombination to replication of UV-irradiated herpes simplex virus type 1Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cellsDifferential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links.DNA interstrand crosslink repair in mammalian cells: step by step.Coordinating DNA polymerase traffic during high and low fidelity synthesis.The role of hRev7, the accessory subunit of hPolζ, in translesion synthesis past DNA damage induced by benzo[a]pyrene diol epoxide (BPDE)DNA polymerases in the mitochondria: A critical review of the evidence.Coordinated protein and DNA remodeling by human HLTF on stalled replication forkPCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana.Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass.Role of the ubiquitin-binding domain of Polη in Rad18-independent translesion DNA synthesis in human cell extracts.Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet lightRev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation.Loss of DNA polymerase zeta enhances spontaneous tumorigenesis.Analysis of CPD ultraviolet lesion bypass in chicken DT40 cells: polymerase η and PCNA ubiquitylation play identical rolesIdentification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity.Analysis of the tolerance to DNA alkylating damage in MEC1 and RAD53 checkpoint mutants of Saccharomyces cerevisiae.Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy.Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sitesDNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes.REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ
P2860
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P2860
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@ast
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@en
type
label
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@ast
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@en
prefLabel
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@ast
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@en
P2093
P2860
P356
P1433
P1476
Two-polymerase mechanisms dict ...... esion DNA synthesis in mammals
@en
P2093
Errol C Friedberg
John Wittschieben
Nicholas Geacintov
Sharon Avkin
Sheera Adar
Sigal Shachar
Stephen Chaney
Thomas Reissner
Zhigang Wang
Zvi Livneh
P2860
P304
P356
10.1038/EMBOJ.2008.281
P407
P577
2009-01-15T00:00:00Z