Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs.
about
Synthetic biology in mammalian cells: next generation research tools and therapeuticsDREADDs: novel tools for drug discovery and developmentEpigenetic mechanisms in mood disorders: targeting neuroplasticityHypothalamic control of male aggression-seeking behavior.Tracking the Time-Dependent Role of the Hippocampus in Memory Recall Using DREADDsOptogenetic and Chemogenetic Approaches for Studying Astrocytes and GliotransmittersPharmacosynthetics: Reimagining the pharmacogenetic approachAllosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.Annual Research Review: Transgenic mouse models of childhood-onset psychiatric disorders.Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use.Inducible control of gene expression with destabilized Cre.Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions.Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP SignalingFoundations for the design and implementation of synthetic genetic circuits.Assessing neurocognitive function in psychiatric disorders: a roadmap for enhancing consensus.Remote control of neuronal signaling.A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.High throughput engineering to revitalize a vestigial electron transfer pathway in bacterial photosynthetic reaction centersContemporary approaches to neural circuit manipulation and mapping: focus on reward and addiction.Modulating and evaluating receptor promiscuity through directed evolution and modeling.Serotype-dependent transduction efficiencies of recombinant adeno-associated viral vectors in monkey neocortexDREADDs for Neuroscientists.Promoter-Specific Effects of DREADD Modulation on Hippocampal Synaptic Plasticity and Memory Formation.Functional wiring of hypocretin and LC-NE neurons: implications for arousalNovel designer receptors to probe GPCR signaling and physiologyShining light on wakefulness and arousal.Striatal mechanisms underlying movement, reinforcement, and punishment.Activation of the Hypoglossal to Tongue Musculature Motor Pathway by Remote Control.Unparalleled control of neural activity using orthogonal pharmacogenetics.New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.Are we getting closer to valid translational models for major depression?New tricks for old dogmas: optogenetic and designer receptor insights for Parkinson's diseaseUnraveling the central proopiomelanocortin neural circuits.Molecular approaches for manipulating astrocytic signaling in vivo.The Corticohippocampal Circuit, Synaptic Plasticity, and Memory.Synthetic biology: applying biological circuits beyond novel therapies.The Pharmacology and Function of Receptors for Short-Chain Fatty Acids.A morphospace for synthetic organs and organoids: the possible and the actual.Reprogramming cellular functions with engineered membrane proteins.Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a receptor activated solely by synthetic ligand (RASSL).
P2860
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P2860
Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Directed molecular evolution o ...... eating next-generation RASSLs.
@ast
Directed molecular evolution o ...... eating next-generation RASSLs.
@en
Directed molecular evolution o ...... eating next-generation RASSLs.
@nl
type
label
Directed molecular evolution o ...... eating next-generation RASSLs.
@ast
Directed molecular evolution o ...... eating next-generation RASSLs.
@en
Directed molecular evolution o ...... eating next-generation RASSLs.
@nl
prefLabel
Directed molecular evolution o ...... eating next-generation RASSLs.
@ast
Directed molecular evolution o ...... eating next-generation RASSLs.
@en
Directed molecular evolution o ...... eating next-generation RASSLs.
@nl
P2860
P356
P1433
P1476
Directed molecular evolution o ...... eating next-generation RASSLs.
@en
P2093
Bryan L Roth
Sarah C Rogan
P2860
P2888
P304
P356
10.1038/NPROT.2009.239
P50
P577
2010-02-25T00:00:00Z
P6179
1028575808