Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression. - Wikidata - thesis-toulmin - TriplyDB

Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.

Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.

http://www.wikidata.org/entity/Q33553226

about

Osteopontin-A Master Regulator of Epithelial-Mesenchymal Transition Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.Roles for the type III TGF-beta receptor in human cancer Immunohistochemical expression of epithelial and stromal immunomodulatory signalling molecules is a prognostic indicator in breast cancer.Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows Hormonal induction and roles of Disabled-2 in lactation and involution.A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland The mammary gland microenvironment directs progenitor cell fate in vivo Association of TGF-β2 levels in breast milk with severity of breast biopsy diagnosis.Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution.Mammary gland involution as an immunotherapeutic target for postpartum breast cancer.High incidence of triple negative breast cancers following pregnancy and an associated gene expression signature.Singleminded-2s (Sim2s) promotes delayed involution of the mouse mammary gland through suppression of Stat3 and NFκB An "elite hacker": breast tumors exploit the normal microenvironment program to instruct their progression and biological diversity.Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization.Mouse mammary gland is refractory to the effects of ethanol after natural lactation.The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland.Bronchioloalveolar invasion in non-small cell lung cancer is associated with expression of transforming growth factor-β1 A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.Generation of mice with a conditional allele for the transforming growth factor beta3 gene.Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium.Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution.Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer.The role of activin in mammary gland development and oncogenesis.Involvement of Different networks in mammary gland involution after the pregnancy/lactation cycle: Implications in breast cancer.Targeting TGF-β Signaling for Therapeutic Gain.Regulation of epithelial to mesenchymal transition: CK2β on stage.Decrease of lactogenic hormones induce epithelial-mesenchymal transition via TGFβ1 and arachidonic acid during mammary gland involution.Negative feedback loop between ZBTB7A and TGF-β in breast cancer.TGF-β induction of FGF-2 expression in stromal cells requires integrated smad3 and MAPK pathways.Inhibition of dendritic cell migration by transforming growth factor-β1 increases tumor-draining lymph node metastasis.Premature mammary gland involution with repeated corticosterone injection in interleukin 10-deficient mice.Histology and Transcriptome Profiles of the Mammary Gland across Critical Windows of Development in Sprague Dawley Rats

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Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression.

http://www.wikidata.org/entity/Q33553226

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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Kathleen C Flanders

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P2860

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

Inhibition of translation of transforming growth factor-beta 3 mRNA by its 5' untranslated region

Transforming growth factor-beta complexes with thrombospondin

The epithelial-mesenchymal transition generates cells with properties of stem cells

Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix

Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3

Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

Gene expression profiling predicts clinical outcome of breast cancer

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth

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