Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. - Wikidata - thesis-toulmin - TriplyDB

Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.

Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.

http://www.wikidata.org/entity/Q33567678

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Regulation of fear extinction versus other affective behaviors by discrete cortical scaffolding complexes associated with NR2B and PKA signaling Regulation of the phosphatase PP2B by protein-protein interactions Subcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendrites Anchored phosphatases modulate glucose homeostasis Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation A presynaptic role for PKA in synaptic tagging and memory.Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons AKAP79/150 impacts intrinsic excitability of hippocampal neurons through phospho-regulation of A-type K+ channel trafficking.Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2.A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density.AKAPs: the architectural underpinnings of local cAMP signaling.AKAP12 and AKAP5 form higher-order hetero-oligomers.A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors.Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms.Protein Kinase C (PKC)ζ Pseudosubstrate Inhibitor Peptide Promiscuously Binds PKC Family Isoforms and Disrupts Conventional PKC Targeting and Translocation.A-kinase anchoring proteins as potential drug targets.Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation "Shaping" of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor.AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.Muscle A-Kinase Anchoring Protein-α is an Injury-Specific Signaling Scaffold Required for Neurotrophic- and Cyclic Adenosine Monophosphate-Mediated Survival Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory.Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation.Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic β-adrenergic signaling.AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction.NMDA Receptor-Dependent LTD Requires Transient Synaptic Incorporation of Ca²⁺-Permeable AMPARs Mediated by AKAP150-Anchored PKA and Calcineurin Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination.Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain.Selective expression of a dominant-negative type Iα PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity.AKAP signaling complexes in regulation of excitatory synaptic plasticity A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases.Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity.AKAP-anchored PKA maintains neuronal L-type calcium channel activity and NFAT transcriptional signaling.Activity-dependent transcriptional regulation of M-Type (Kv7) K(+) channels by AKAP79/150-mediated NFAT actions.Identification of a signaling cascade that maintains constitutive δ-opioid receptor incompetence in peripheral sensory neurons.Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.A-Kinase Anchoring Protein 150 (AKAP150) Promotes Cocaine Reinstatement by Increasing AMPA Receptor Transmission in the Accumbens Shell.Potential for therapeutic targeting of AKAP signaling complexes in nervous system disorders.Sensitizing exposure to amphetamine increases AMPA receptor phosphorylation without increasing cell surface expression in the rat nucleus accumbens.

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P2860

Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.

http://www.wikidata.org/entity/Q33567678

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@ast

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@en

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@nl

type

label

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@ast

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@en

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@nl

prefLabel

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@ast

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@en

Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

@nl

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Mutations in AKAP5 disrupt den ...... behavioral phenotypes in mice.

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C Blake Nichols

http://www.w3.org/2001/XMLSchema#string

G Stanley McKnight

http://www.w3.org/2001/XMLSchema#string

Johannes W Hell

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Linghai Yang

http://www.w3.org/2001/XMLSchema#string

Margaret L Allen

http://www.w3.org/2001/XMLSchema#string

Michael Weisenhaus

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Thomas Su

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Yuan Lu

http://www.w3.org/2001/XMLSchema#string

P2860

Long-Term Potentiation and Memory

Targeting of an A kinase-anchoring protein, AKAP79, to an inwardly rectifying potassium channel, Kir2.1

Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins

Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice

Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling

Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding

Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms

Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex

Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95

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20428246

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electrophysiology

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2859064

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