Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer - Wikidata - thesis-toulmin - TriplyDB

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

http://www.wikidata.org/entity/Q33591673

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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cells Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73 Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion Apoptotic pathways as a therapeutic target for colorectal cancer treatment Biomarkers and Targeted Therapy in Pancreatic Cancer The Contrived Mutant p53 Oncogene - Beyond Loss of Functions Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer GEMMs as preclinical models for testing pancreatic cancer therapies Evolution and dynamics of pancreatic cancer progression Molecular mechanism underlying lymphatic metastasis in pancreatic cancer Pancreatic cancer A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion The rebel angel: mutant p53 as the driving oncogene in breast cancer.Therapeutic potential of targeting acinar cell reprogramming in pancreatic cancer Tall cell variant of papillary thyroid carcinoma: current evidence on clinicopathologic features and molecular biology Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2.Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53 Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion.Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.The use of multidimensional data to identify the molecular biomarker for pancreatic ductal adenocarcinoma.Bayesian pathway analysis of cancer microarray data.Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward.OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation.Clinical update on cancer: molecular oncology of head and neck cancer Degradation of mutant p53H175 protein by Zn(II) through autophagy.Assessing the Racial and Ethnic Disparities in Breast Cancer Mortality in the United States Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation A complex secretory program orchestrated by the inflammasome controls paracrine senescence.Macromolecular therapeutics Targeting mTOR dependency in pancreatic cancer Therapeutic options for the management of pancreatic cancer.The role of mutant p53 in human cancer.Imaging molecular dynamics in vivo--from cell biology to animal models.AKT regulates NPM dependent ARF localization and p53mut stability in tumors.Epigenetic linkage of aging, cancer and nutrition.The expression and clinical significance of ribophorin II (RPN2) in human breast cancer.

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P2860

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

http://www.wikidata.org/entity/Q33591673

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

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Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

@en

type

label

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

@ast

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

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prefLabel

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

@ast

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

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PNAS.0908428107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

@en

P2093

Andrew M Lowy

http://www.w3.org/2001/XMLSchema#string

Brendan Doyle

http://www.w3.org/2001/XMLSchema#string

Karin A Oien

http://www.w3.org/2001/XMLSchema#string

Nigel B Jamieson

http://www.w3.org/2001/XMLSchema#string

Paul Timpson

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Rachel A Ridgway

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Saadia A Karim

http://www.w3.org/2001/XMLSchema#string

T R Jeffry Evans

http://www.w3.org/2001/XMLSchema#string

Valerie G Brunton

http://www.w3.org/2001/XMLSchema#string

P2860

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

WAF1, a potential mediator of p53 tumor suppression

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

Chemokine signaling via the CXCR2 receptor reinforces senescence

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

P304

246-251

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scholarly article

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10.1073/PNAS.0908428107

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1

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107

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Jennifer P. Morton

Dimitris Athineos

Margaret C Frame

P577

2009-12-14T00:00:00Z

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40696085

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20018721

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2806749

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