The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis
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Tissue Factor-Factor VII Complex As a Key Regulator of Ovarian Cancer PhenotypesEndometriosis, angiogenesis and tissue factorTargeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice.Novel therapies targeting endometriosisNatural killer cells are crucial for the efficacy of Icon (factor VII/human IgG1 Fc) immunotherapy in human tongue cancerhI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma.Anti-angiogenic treatment strategies for the therapy of endometriosis.Development and prevention of postsurgical adhesions in a chimeric mouse model of experimental endometriosis.Effective treatment of chemoresistant breast cancer in vitro and in vivo by a factor VII-targeted photodynamic therapy.Proangiogenic Tie2(+) macrophages infiltrate human and murine endometriotic lesions and dictate their growth in a mouse model of the disease.Induction of endometriosis alters the peripheral and endometrial regulatory T cell population in the non-human primate.Dietary fish oil supplementation inhibits formation of endometriosis-associated adhesions in a chimeric mouse modelEffects of simvastatin on retinoic acid system in primary human endometrial stromal cells and in a chimeric model of human endometriosis.Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor.Molecular blockade of angiogenic factors: A new therapeutic tool for the treatment of abnormal uterine bleedingThe role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding.Selective and effective killing of angiogenic vascular endothelial cells and cancer cells by targeting tissue factor using a factor VII-targeted photodynamic therapy for breast cancer.Tissue factor is an angiogenic-specific receptor for factor VII-targeted immunotherapy and photodynamic therapy.Role of tissue factor in feto-maternal development: a xiphos.Immunological aspects of endometriosis: an update.Tissue factor pathway inhibitor: structure-function.Experimental treatments of endometriosis.An overview of early drug development for endometriosis.Therapeutically Targeting the Inflammasome Product in a Chimeric Model of Endometriosis-Related Surgical Adhesions.Progesterone utilizes distinct membrane pools of tissue factor to increase coagulation and invasion and these effects are inhibited by TFPI.Evidence for a Hypercoagulable State in Women With Ovarian Endometriomas.Targeting Tissue Factor for Immunotherapy of Triple-Negative Breast Cancer Using a Second-Generation ICON.Endometriosis-Derived Stromal Cells Secrete Thrombin and Thromboxane A2, Inducing Platelet Activation.The role of tissue factor and protease-activated receptor 2 in endometriosis.Rodent Models of Experimental Endometriosis: Identifying Mechanisms of Disease and Therapeutic Targets.[Advances of tissue factor in lung cancer].
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P2860
The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@ast
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@en
type
label
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@ast
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@en
prefLabel
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@ast
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@en
P2093
P2860
P1476
The immunoconjugate "icon" tar ...... ng regression of endometriosis
@en
P2093
Alan Garen
Carmen J Booth
Charles J Lockwood
Felice Arcuri
Frederick Schatz
Graciela Krikun
Hugh S Taylor
Kaylon L Bruner-Tran
Kevin Osteen
William Konigsberg
P2860
P304
P356
10.2353/AJPATH.2010.090757
P407
P577
2009-12-30T00:00:00Z