p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity - Wikidata - thesis-toulmin - TriplyDB

p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity

p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity

http://www.wikidata.org/entity/Q33696861

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p53 opens the mitochondrial permeability transition pore to trigger necrosis PUMA, a potent killer with or without p53 The Roles of Syncytin-Like Proteins in Ruminant Placentation Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease.BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain.Anti-cancer agents in Saudi Arabian herbals revealed by automated high-content imaging.Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications.Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress.BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition?BH3-only proteins in apoptosis and beyond: an overview.GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria.p53 is required for cisplatin-induced processing of the mitochondrial fusion protein L-Opa1 that is mediated by the mitochondrial metallopeptidase Oma1 in gynecologic cancers Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer.Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma.Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101.A New Fungal Diterpene Induces VDAC1-dependent Apoptosis in Bax/Bak-deficient Cells.Heat stress induced apoptosis is triggered by transcription-independent p53, Ca(2+) dyshomeostasis and the subsequent Bax mitochondrial translocation.Increased sensitivity of African American triple negative breast cancer cells to nitric oxide-induced mitochondria-mediated apoptosis.It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53.Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53 The mitochondrial p53 pathway.p53 polymorphisms: cancer implications.Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model.Cytoplasmic functions of the tumour suppressor p53.Heat stress induces apoptosis through transcription-independent p53-mediated mitochondrial pathways in human umbilical vein endothelial cell.The cell death machinery governed by the p53 tumor suppressor in response to DNA damage.Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria.The relevance of protein-protein interactions for p53 function: the CPE contribution.Programmed cell death in Parkinson's disease PUMA, a critical mediator of cell death--one decade on from its discovery.The cytoplasmic side of p53's oncosuppressive activities.Role of the nucleus in apoptosis: signaling and execution.Modulation of p53 during bacterial infections.A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems.Mitochondrial death functions of p53.

P2860

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P2860

p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity

http://www.wikidata.org/entity/Q33696861

description

2008 nî lūn-bûn

@nan

2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

p53's mitochondrial translocat ...... tochondrial membrane integrity

@ast

p53's mitochondrial translocat ...... tochondrial membrane integrity

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type

label

p53's mitochondrial translocat ...... tochondrial membrane integrity

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p53's mitochondrial translocat ...... tochondrial membrane integrity

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prefLabel

p53's mitochondrial translocat ...... tochondrial membrane integrity

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p53's mitochondrial translocat ...... tochondrial membrane integrity

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p53's mitochondrial translocat ...... tochondrial membrane integrity

@en

P2093

Gustavo Palacios

http://www.w3.org/2001/XMLSchema#string

Sonja Wolff

http://www.w3.org/2001/XMLSchema#string

Susan Erster

http://www.w3.org/2001/XMLSchema#string

Ute M Moll

http://www.w3.org/2001/XMLSchema#string

P2860

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

p53 has a direct apoptogenic role at the mitochondria

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

P2888

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733-744

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scholarly article

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10.1038/CR.2008.62

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7

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18

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2008-07-01T00:00:00Z

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18504456

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2830652

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