Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies
about
Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitusMolecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins.Multi-layered molecular mechanisms of polypeptide holding, unfolding and disaggregation by HSP70/HSP110 chaperonesHeat shock proteins: a therapeutic target worth to consider.Promoting Neuronal Tolerance of Diabetic Stress: Modulating Molecular Chaperones.Genetic association of NOS1 exon18, NOS1 exon29, ABCB1 1236C/T, and ABCB1 3435C/T polymorphisms with the risk of Parkinson's disease: A meta-analysis.Identification of chaperones in a MPP+-induced and ATRA/TPA-differentiated SH-SY5Y cell PD model.Aberrant autophagy and parkinsonism: does correction rescue from disease progression?The chaperone Grp78 in protein folding disorders of the nervous system.Lamotrigine Attenuates Proteasome Inhibition-Induced Apoptosis by Suppressing the Activation of the Mitochondrial Pathway and the Caspase-8- and Bid-Dependent Pathways.RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology.Protein misfolding diseases: prospects of pharmacological treatment.Chaperone-Based Therapies for Disease Modification in Parkinson's Disease.Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes.Apigenin Reduces Proteasome Inhibition-Induced Neuronal Apoptosis by Suppressing the Cell Death Process.Flavanonol taxifolin attenuates proteasome inhibition-induced apoptosis in differentiated PC12 cells by suppressing cell death process.3,4,5-tricaffeoylquinic acid attenuates proteasome inhibition-mediated programmed cell death in differentiated PC12 cells.Development of noviomimetics that modulate molecular chaperones and manifest neuroprotective effects.Molecular Chaperones in Neurodegenerative Diseases: A Short Review.Pla2g6 Deficiency in Zebrafish Leads to Dopaminergic Cell Death, Axonal Degeneration, Increased β-Synuclein Expression, and Defects in Brain Functions and Pathways.Hepatitis C virus NS5A protein promotes the lysosomal degradation of hepatocyte nuclear factor 1α via chaperone-mediated autophagy.Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology.A Rationally Designed Hsp70 Variant Rescues the Aggregation-Associated Toxicity of Human IAPP in Cultured Pancreatic Islet β-Cells.Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy.HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neuronsAmyloid assembly and disassembly
P2860
Q27322513-383F2B47-A866-497A-9D78-573E01C91112Q28397425-22B73B52-5B8C-4E57-93C3-D48793FC2A8FQ34038270-BE19F35A-06AF-498A-99FF-1966DB4CEB90Q35686747-75696C27-BA38-4F40-92E1-54CBEE0F29AEQ36650202-54EF7385-352A-4ADD-B21D-A39853EEF08EQ37057856-EF4D085F-F7E2-4DA4-BB53-AB6F88468CCFQ37328854-35D8FFB4-30F0-468A-BFD5-827A75CD727DQ37553863-93A0E81B-E2A8-4022-876A-F105549B9C8CQ38212199-97D44B67-D615-4F3A-B023-E447D2479741Q38238281-E10665EB-5E69-4E39-B775-C9909BC992C4Q38768222-C99E9B21-9B50-4C28-8268-CCBBA27FCD33Q38788619-FF2C2E20-7746-4C8C-AF56-105C8C605443Q39410882-877DBF52-2BA9-4054-82D5-7EDF9924C38CQ41623081-870BCB45-8C0D-483E-AD94-3A449F12522BQ42066873-0B2DF585-7F41-4AF9-8DFA-484B405E3113Q46465668-2A039957-49FB-4231-8D14-2C18803CD3F7Q46802646-A87B6917-784E-40C3-82E4-7770C759056CQ46894541-88AFF75B-07B0-4318-A909-F60B856E8520Q47403043-66168762-7FE9-493F-A747-E62487FCEB62Q47710921-B60BB71E-6DA4-4614-BDCE-4C52B5EBF9EEQ47854549-167BD777-7361-4B7C-AF04-2853078F337DQ52716681-5D2D70DE-F8DA-4729-9E39-A3590692F9BBQ55003043-C554C973-D419-404D-857D-B311ED2D72F3Q55032468-B0F8F479-BF77-4DE4-9D60-9D6FE812F752Q55617564-19C9366B-B5C1-413B-BFF2-93A933015C49Q57810923-12B1CF70-853B-477F-AFFE-BFAADB3E08A8Q58621641-19107AC2-1AB2-435A-B209-65CF25788E08
P2860
Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Molecular chaperones and prote ...... se and other synucleinopathies
@ast
Molecular chaperones and prote ...... se and other synucleinopathies
@en
type
label
Molecular chaperones and prote ...... se and other synucleinopathies
@ast
Molecular chaperones and prote ...... se and other synucleinopathies
@en
prefLabel
Molecular chaperones and prote ...... se and other synucleinopathies
@ast
Molecular chaperones and prote ...... se and other synucleinopathies
@en
P2860
P921
P356
P1476
Molecular chaperones and prote ...... se and other synucleinopathies
@en
P2093
Laiq-Jan Saidi
P2860
P2888
P356
10.1186/2051-5960-1-79
P5008
P577
2013-12-05T00:00:00Z
P5875
P6179
1040131182