Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease - Wikidata - thesis-toulmin - TriplyDB

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

http://www.wikidata.org/entity/Q33726762

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7,8-Dihydroxyflavone, a small molecule TrkB agonist, improves spatial memory and increases thin spine density in a mouse model of Alzheimer disease-like neuronal loss 7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders Spatio-temporal expression of a novel neuron-derived neurotrophic factor (NDNF) in mouse brains during development Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice MAO-inhibitors in Parkinson's Disease Postischemic PKC activation rescues retrograde and anterograde long-term memory Neural stem/progenitor cells in Alzheimer's disease Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders Alzheimer's Disease: Mechanism and Approach to Cell Therapy Potential therapeutic effects of neurotrophins for acute and chronic neurological diseases Involvement of long noncoding RNAs in diseases affecting the central nervous system Current concept in neural regeneration research: NSCs isolation, characterization and transplantation in various neurodegenerative diseases and stroke: A review New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits Entorhinal cortical defects in Tg2576 mice are present as early as 2-4 months of age.In vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer's Disease.Stem cells in human neurodegenerative disorders--time for clinical translation?Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model.Impairment of TrkB-PSD-95 signaling in Angelman syndrome NDRG4 protein-deficient mice exhibit spatial learning deficits and vulnerabilities to cerebral ischemia Identification of BDNF sensitive electrophysiological markers of synaptic activity and their structural correlates in healthy subjects using a genetic approach utilizing the functional BDNF Val66Met polymorphism.Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model.Down-regulation of serum gonadotropins but not estrogen replacement improves cognition in aged-ovariectomized 3xTg AD female mice The pro-domains of neurotrophins, including BDNF, are linked to Alzheimer's disease through a toxic synergy with Aβ Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness.FEASIBILITY STUDY OF A CLINICAL BLOOD-BRAIN BARRIER OPENING ULTRASOUND SYSTEM.Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles.Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?Localization of BDNF mRNA with the Huntington's disease protein in rat brain.Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network.Silencing PP2A inhibitor by lenti-shRNA interference ameliorates neuropathologies and memory deficits in tg2576 mice.Human neural stem cells alleviate Alzheimer-like pathology in a mouse model.A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status Epilepticus

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Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

http://www.wikidata.org/entity/Q33726762

description

2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Neuroprotective effects of bra ...... models of Alzheimer's disease

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Nature Medicine

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Neuroprotective effects of bra ...... models of Alzheimer's disease

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Alan H Nagahara

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Albert Kim

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Andrea A Chiba

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Brock E Schroeder

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Daniel Geschwind

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Edward H Koo

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Gideon M Shaked

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Giovanni Coppola

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James M Conner

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Ling Wang

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Molecular markers of early Parkinson's disease based on gene expression in blood

Functional recovery in parkinsonian monkeys treated with GDNF

Neurotrophin signal transduction in the nervous system.

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches.

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.

Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man.

Caspase Activation in the Alzheimer's Disease Brain: Tortuous and Torturous.

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331-337

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scholarly article

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10.1038/NM.1912

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3

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15

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Eliezer Masliah

Edward Rockenstein

David A Merrill

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2009-02-08T00:00:00Z

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23986116

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1042601638

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19198615

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Alzheimer's disease

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2838375

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