PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein. - Wikidata - thesis-toulmin - TriplyDB

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

http://www.wikidata.org/entity/Q33773594

about

Spontaneous inward opening of the dopamine transporter is triggered by PIP2-regulated dynamics of the N-terminus Mapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular Dynamics The rare DAT coding variant Val559 perturbs DA neuron function, changes behavior, and alters in vivo responses to psychostimulants.Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter.Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters.Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency Insights in how amphetamine ROCKs (Rho-associated containing kinase) membrane protein trafficking.Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2 -containing membranes.Regulation of the Dopamine and Vesicular Monoamine Transporters: Pharmacological Targets and Implications for Disease.Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors.Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII.Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission.Functional mechanisms of neurotransmitter transporters regulated by lipid-protein interactions of their terminal loops.Amphetamines, new psychoactive drugs and the monoamine transporter cycle.Molecular overlap in the regulation of SK channels by small molecules and phosphoinositides Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant.A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter.Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities.Phospho-specific antibodies targeting the amino terminus of the human dopamine transporter.HIV, Tat and dopamine transmission.Atypical dopamine efflux caused by 3,4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter.Lipids modulate the conformational dynamics of a secondary multidrug transporter.The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids.The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter.PKCβ Inhibitors Attenuate Amphetamine-Stimulated Dopamine Efflux.Gβγ subunit activation promotes dopamine efflux through the dopamine transporter.A kinetic account for amphetamine-induced monoamine release.Dimer Interface of the Human Serotonin Transporter and Effect of the Membrane Composition.A Fly's Eye View of Natural and Drug Reward.Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter.How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties.Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain.

P2860

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P2860

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

http://www.wikidata.org/entity/Q33773594

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

@zh-tw

2014年论文

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name

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

@ast

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

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type

label

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

@ast

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

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prefLabel

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

@ast

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

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P1433

Nature Chemical Biology

P1476

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein

@en

P2093

Andrea N Belovich

http://www.w3.org/2001/XMLSchema#string

Aurelio Galli

http://www.w3.org/2001/XMLSchema#string

Christine Saunders

http://www.w3.org/2001/XMLSchema#string

George Khelashvili

http://www.w3.org/2001/XMLSchema#string

Kevin Erreger

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Peter J Hamilton

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P2860

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

The binding sites for cocaine and dopamine in the dopamine transporter overlap

N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux

Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium

VMD: visual molecular dynamics

Comparative protein modelling by satisfaction of spatial restraints

Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux.

Mechanisms of neurotransmitter release by amphetamines: a review

PIP2 and PIP3: complex roles at the cell surface

P2888

P304

582-589

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scholarly article

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10.1038/NCHEMBIO.1545

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P433

7

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P478

10

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P50

Jonathan Javitch

Heinrich J Matthies

Harel Weinstein

P577

2014-06-01T00:00:00Z

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P5875

262783541

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24880859

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4062427

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